Linezolid oral/injection

Generic name: Linezolid (oral/injection)
Brand names: Zyvox
Drug class: Oxazolidinone antibiotics

Usage of Linezolid oral/injection

Linezolid is an antibiotic that fights bacteria in the body. Linezolid is also an MAO (monoamine oxidase) inhibitor.

Linezolid is used to treat different types of bacterial infections, such as pneumonia, skin infections, and infections that are resistant to other antibiotics.

Linezolid may also be used for purposes not listed in this medication guide.

Linezolid oral/injection side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Linezolid may cause serious side effects. Call your doctor at once if you have:

vision problems, changes in color vision;

severe stomach pain, diarrhea that is watery or bloody;

a seizure;

sweating, feeling anxious or shaky (may be signs of low blood sugar);

lactic acidosis--unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or

low blood cell counts--fever, chills, tiredness, weakness, confusion, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of linezolid may include:

nausea, vomiting, diarrhea;

rash;

anemia (low red blood cells); or

headache, dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Linezolid oral/injection

You should not use linezolid if you are allergic to it.

Do not use linezolid if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with linezolid could cause a serious condition called serotonin syndrome.

Tell your doctor if you have ever had:

high blood pressure;

a thyroid disorder;

a carcinoid tumor;

bone marrow suppression or a weak immune system;

kidney or liver disease;

pheochromocytoma (adrenal gland tumor);

diabetes;

seizures; or

if you use a catheter.

Tell your doctor if you are pregnant or breastfeeding.

If you are breastfeeding, tell your doctor if you notice diarrhea or vomiting in the nursing baby.

Linezolid liquid may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

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How to use Linezolid oral/injection

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Linezolid oral is taken by mouth.

Linezolid tablets or liquid can be taken with or without food.

Gently mix the oral suspension (liquid) by turning the bottle upside down 3 to 5 times. Do not shake. Measure a dose with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Linezolid injection is given in a vein.

Read and follow all Instructions for Use. Ask your doctor or pharmacist if you need help.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

You will need frequent medical tests. Your vision and blood pressure may also need to be checked often.

Keep using linezolid even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Linezolid will not treat a viral infection (flu or a common cold).

Store all forms of linezolid at room temperature away from moisture, heat, and light. Do not freeze. Throw away any liquid not used within 21 days.

Warnings

Some medicines can cause unwanted or dangerous effects when used with linezolid. Tell your doctor about all other medicines you use.

Do not use linezolid if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

What other drugs will affect Linezolid oral/injection

Many drugs can affect linezolid, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.