Lodosyn

Generic name: Carbidopa
Drug class: Dopaminergic antiparkinsonism agents

Usage of Lodosyn

Lodosyn is used with another medicine called levodopa to treat symptoms of Parkinson's disease, such as stiffness or tremors.

Lodosyn and levodopa are also used to treat Parkinson-like symptoms caused by taking certain medicines or by exposure to poisonous gases or minerals such as carbon monoxide or manganese.

Lodosyn is only used in combination with levodopa and has no effect when used alone.

Lodosyn may also be used for purposes not listed in this medication guide.

Lodosyn side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

The following side effects may occur when Lodosyn is taken with levodopa.

Lodosyn may cause serious side effects. Call your doctor at once if you have:

severe drowsiness;

uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);

worsening of tremors (uncontrolled shaking);

severe nausea, vomiting, or diarrhea;

confusion, hallucinations, unusual changes in mood or behavior;

depression or suicidal thoughts;

seizure (convulsions); or

severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Some people taking Lodosyn with levodopa have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking Lodosyn. Talk with your doctor if this occurs.

You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.

Common side effects of Lodosyn may include:

nausea, upset stomach;

headache, dizziness;

sleep problems (insomnia), dreaming more than usual;

dry mouth, burning feeling in your tongue;

weight changes; or

abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Lodosyn

You should not use Lodosyn if you are allergic to it, or if you have:

narrow-angle glaucoma.

Do not use Lodosyn if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you have ever had:

nausea and vomiting while taking levodopa;

heart disease, high blood pressure;

liver or kidney disease;

a stomach or intestinal ulcer;

glaucoma; or

depression, mental illness, or psychosis.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Ask your doctor about skin symptoms to watch for.

It is not known if Lodosyn will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Lodosyn.

Not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Lodosyn

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

If you already take levodopa but have never taken Lodosyn, start taking both medicines at least 12 hours after you last took levodopa by itself.

Take both Lodosyn and levodopa together at regular intervals, to keep steady amounts in your body at all times.

You may need frequent medical tests.

Your symptoms may not improve for several weeks. Call your doctor if your symptoms do not improve or if the effects of this medicine wear off quickly between doses.

You may have withdrawal symptoms if you stop using Lodosyn suddenly. Ask your doctor before stopping the medicine.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Lodosyn.

Store at room temperature away from moisture and heat.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

What other drugs will affect Lodosyn

Using Lodosyn with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect Lodosyn, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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