Lucemyra

Generic name: Lofexidine
Drug class: Antiadrenergic agents , Antineoplastic Agents

Usage of Lucemyra

Lucemyra works by blocking the release of norepinephrine, a hormone similar to adrenaline that contributes to opioid withdrawal symptoms.

Lucemyra is used to reduce opioid withdrawal symptoms after you stop taking an opioid suddenly.

Lucemyra will not treat opioid addiction.

Lucemyra side effects

Get emergency medical help if you have signs of an allergic reaction to Lucemyra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

slow heartbeats;

severe dizziness or drowsiness; or

a light-headed feeling, like you might pass out.

Common Lucemyra side effects may include:

low blood pressure;

dizziness (especially when standing up);

drowsiness; or

dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Lucemyra

You should not use Lucemyra if you are allergic to lofexidine.

Tell your doctor if you have ever had:

slow heartbeats;

low blood pressure;

heart problems;

a heart attack or stroke;

an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

long QT syndrome (in you or a family member);

kidney disease; or

liver disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Lucemyra is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Lucemyra

Usual Adult Dose for Opiate Withdrawal:

Initial dose: 0.54 mg orally 4 times a day during period of peak withdrawal -Dosing should be guided by symptoms and side effects Frequency of dosing: Every 5 to 6 hours Maximum single dose: 0.72 mg Maximum daily dose: 2.88 mg/day Maximum duration of therapy: 14 days Comments: -The period of peak withdrawal symptoms is generally the first 5 to 7 days following last use of opioid. -Treatment may be continued for up to 14 days with dosing guided by symptoms; lower doses may be appropriate as opioid withdrawal symptoms wane. -Discontinuation should occur over a 2 to 4-day period to mitigate withdrawal effects of lofexidine (e.g. reducing by 1 tablet per dose every 1 to 2 days). Use: For the mitigation of opioid withdrawal symptoms to facilitate abrupt opioid discontinuation.

Warnings

Lucemyra can cause serious side effects on your heart or blood vessels. Call your doctor at once if you have slow heartbeats, severe dizziness, or if you feel faint. Do not take another dose of lofexidine until you have talked to your doctor.

Avoid becoming overheated or dehydrated, or you could have very low blood pressure. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

You should not stop using this medicine suddenly. Follow your doctor's instructions about tapering your dose.

What other drugs will affect Lucemyra

Lucemyra can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Using Lucemyra with other drugs that make you drowsy can worsen this effect. Ask your doctor before using a sedative (such as Valium or Xanax), a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may interact with lofexidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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