Lutathera
Generic name: Lutetium Lu 177 Dotatate
Drug class:
Therapeutic radiopharmaceuticals
Usage of Lutathera
Lutathera is a radioactive medicine that binds itself to a specific part of certain tumor cells, allowing the radiation to enter and destroy those cells.
Lutathera is used to treat certain cancers of the digestive tract, including the stomach, pancreas, and intestines.
Lutathera may also be used for purposes not listed in this medication guide.
Lutathera side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Lutathera may cause serious side effects. Call your doctor at once if you have:
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects of Lutathera may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Lutathera
You should not use Lutathera if you are pregnant or breast-feeding.
Lutathera can harm an unborn baby or cause birth defects if the mother or the father is receiving this medicine.
Do not breast-feed while receiving Lutathera, and for at least 4 months after your last dose.
Tell your doctor if you have ever had:
Lutathera may cause other types of cancer, such as leukemia. Ask your doctor about this risk.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because Lutathera may harm the baby if a pregnancy does occur.
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How to use Lutathera
Lutathera is given as an infusion into a vein. A healthcare provider will give you this injection once every 8 weeks for a total of 4 doses.
Lutathera must be given slowly, and the infusion can take 30 to 40 minutes to complete.
After each infusion, you will be given another medicine called octreotide, which is injected into a muscle. Octreotide injections are usually given once every 4 weeks for up to 18 months.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
Drink plenty of fluids while being treated with this medicine. You should urinate often, to help keep your kidneys working properly.
You will need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.
For up to 30 days after you are treated with Lutathera, your urine will contain radiation. To prevent the spread of this radiation, use a toilet rather than a urinal, and sit on the toilet while urinating.
Always wash your hands after using the bathroom. Avoid handling any clean-up of your stools or urine without wearing latex rubber gloves. If another person is handling your urine, they should wear gloves, eye protection, and a mask to cover the nose and mouth.
When cleaning any spills of bodily fluid, use only disposable cleaning cloths that can be flushed down a toilet. Ask your doctor or health department how to dispose of any bodily fluid spills that cannot be flushed down a toilet.
Wash any soiled clothing separately from the laundry of other people in your home.
Warnings
Do not become pregnant or breast-feed a baby while receiving Lutathera.
Both men and women using Lutathera should use effective birth control to prevent pregnancy. Lutathera can harm an unborn baby or cause birth defects if the mother or father is using this medicine.
What other drugs will affect Lutathera
Other drugs may affect Lutathera, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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