Mannitol inhalation

Generic name: Mannitol Inhalation
Drug class: Miscellaneous diuretics

Usage of Mannitol inhalation

Bronchitol is used together with other medicines to improve breathing in adults with cystic fibrosis. Bronchitol is given only after you have passed a tolerance test to make sure you can safely use mannitol inhalation.

Aridol is used as a part of medical testing for asthma in children at least 6 years old.

Mannitol inhalation may also be used for purposes not listed in this medication guide.

Mannitol inhalation side effects

Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mannitol inhalation may cause serious side effects. Call your doctor at once if you have:

  • wheezing, choking, or other breathing problems after using this medicine; or
  • if you cough up large amounts of blood.

    • Common side effects of Bronchitol may include:

  • pain or irritation in your mouth or throat;
  • trouble swallowing;
  • fever; or
  • vomiting.

    • Common side effects of Aridol may include:

  • wheezing, trouble breathing, chest discomfort;
  • cough, throat pain or irritation;
  • runny nose;
  • headache, dizziness; or
  • nausea, vomiting.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Mannitol inhalation

    You should not use this medicine if you've ever had an allergic reaction or bronchospasm (wheezing, chest tightness, trouble breathing) after using mannitol.

    You also should not use this medicine if you are allergic to anything used to make the capsules (such as gelatin, shEllac, isopropyl alcohol, propylene glycol, ammonia solution, titanium dioxide, or iron oxides).

    You should not be treated with Aridol if you have:

  • an aneurysm;
  • untreated or uncontrolled high blood pressure; or
  • a recent heart attack or stroke.

    • Tell your doctor if you have ever had:

  • a severe cough, or a cough with bloody mucus;
  • a collapsed lung or punctured lung;
  • angina (chest pain);
  • surgery on your stomach or chest, or your eyes;
  • if you have ever coughed up blood; or
  • if you have active symptoms of an infection that could affect your lungs (such as stuffy nose, sore throat, fever, chills, cough, chest pain, or trouble breathing).

    • Tell your doctor if you are pregnant or breastfeeding.

    Relate drugs

    How to use Mannitol inhalation

    Usual Adult Dose for Oliguria:

    Renal function test dose prior to initiation of treatment: 0.2 g/kg IV over 3 to 5 min resulting in a urine flow of at least 30 to 50 mL/hr. A second test dose may be administered if the urine flow does not increase. If no response is seen following the second test dose, the patient should be reevaluated.Treatment: 300 to 400 mg/kg (21 to 28 g for a 70 kg patient) or up to 100 g of 15% to 20% solution IV once. Treatment should not be repeated in patients with persistent oliguria.Prevention (for use during cardiovascular and other types of surgery): 50 to 100 g IV. usually a 5 , 10, or 20% solution is used Depending on the fluid requirements of the patient.

    Usual Adult Dose for Cerebral Edema:

    0.25 to 2 g/kg as a 15 to 20% solution IV over at least 30 min administered not more frequently than every 6 to 8 hrs.To yield a satisfactory reduction in intracranial pressure, the osmotic gradient between the blood and cerebrospinal fluid should remain approximately 20 mOsmol.In small &/or debilitated patients 500 mg/kg may be sufficient.

    Warnings

    You should not use mannitol inhalation if you've ever had an allergic reaction or bronchospasm (wheezing, chest tightness, trouble breathing) after using mannitol. You also should not use this medicine if you are allergic to the capsule ingredients.

    What other drugs will affect Mannitol inhalation

    Other drugs may affect mannitol inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

    Disclaimer

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