Maraviroc

Generic name: Maraviroc
Brand names: Selzentry
Drug class: Chemokine receptor antagonist

Usage of Maraviroc

Maraviroc is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Maraviroc is used with other medications to treat CCR5-tropic HIV type 1, a virus that can cause acquired immunodeficiency syndrome (AIDS). Maraviroc is not a cure for HIV or AIDS.

Maraviroc is for use in adults and children who weigh at least 4.4 pounds (2 kilograms).

Maraviroc may also be used for purposes not listed in this medication guide.

Maraviroc side effects

Get emergency medical help if you have signs of an allergic Reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Stop taking maraviroc and seek medical treatment at once if you have a serious drug reaction that can affect many parts of your body (especially your liver). Symptoms may include: itching or rash, fever, swollen glands, muscle or joint aches, severe weakness, unusual bruising, upper stomach pain, vomiting, dark urine, or jaundice (yellowing of the skin or eyes).

Call your doctor at once if you have a side effect such as:

a light-headed feeling, like you might pass out; or

chest pressure, tight feeling in your neck or jaw, sweating, pain spreading to your arm or shoulder.

Maraviroc affects your immune system, which may cause certain side effects (even weeks or months after you've taken maraviroc). Tell your doctor if you have:

signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;

trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or

swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects of maraviroc may include:

fever, cold symptoms, cough;

indigestion, gas, bloating, nausea, vomiting, diarrhea, constipation;

rash;

dizziness; or

(in newborns) abnormal blood tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Maraviroc

If you have severe or end-stage kidney disease, you may not be able to take maraviroc if you use certain medications, including some antibiotics or antifungal medications, some heart or blood pressure medicines, St. John's wort, and certain drugs to treat hepatitis or tuberculosis. Tell your doctor about all other medications you use.

Tell your doctor if you have ever had:

kidney disease (or if you are on dialysis);

liver disease, especially hepatitis B or C;

heart disease; or

low blood pressure.

Maraviroc affects your immune system and may possibly increase your risk of developing infections or cancer. Ask your doctor about this risk.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Maraviroc is not approved for a premature baby, or a child who weighs less than 4.4 pounds (2 kilograms).

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How to use Maraviroc

Before you are treated with maraviroc, your doctor may perform a blood test to make sure maraviroc is the right treatment for your type of HIV.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Maraviroc must be given in combination with other antiviral medications and it should not be used alone.

You may take maraviroc with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Tell your doctor if the child taking maraviroc has trouble swallowing the tablet whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Maraviroc doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store at room temperature away from moisture and heat.

Warnings

If you have severe kidney disease, you may not be able to take maraviroc if you use certain other medications. Tell your doctor about all other medications you use.

Stop taking this medicine and seek medical treatment at once if you have a serious drug reaction that can harm your liver. Symptoms may include: itching or rash, vomiting, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

What other drugs will affect Maraviroc

Sometimes it is not safe to use certain medications at the SAMe time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect maraviroc. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.