Maribavir

Generic name: Maribavir
Brand names: Livtencity
Dosage form: oral tablet (200 mg)
Drug class: Miscellaneous antivirals

Usage of Maribavir

Maribavir is an antiviral medicine used to treat cytomegalovirus (CMV) infection in people 12 years and older weighing at least 77 lbs (35 kg) who have received an organ transplant.

maribavir is used when an infection or disease does not respond to treatment with ganciclovir, valganciclovir, cidofovir or foscarnet.

Maribavir may also be used for purposes not listed in this medication guide.

Maribavir side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Maribavir may cause serious side effects. Call your doctor at once if you have:

  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath.
  • Common side effects of maribavir may include:

  • vomiting, nausea, diarrhea;
  • tiredness; or
  • changes in your sense of taste.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Maribavir

    Tell your doctor if you have:

  • end-stage kidney disease (including if you are on dialysis); or
  • severe liver disease.
  • Some drugs should not be used with maribavir. Your treatment plan may change if you also use: Carbamazepine, phenytoin or phenobarbital.

    Tell your doctor if you are pregnant or breastfeeding.

    Relate drugs

    How to use Maribavir

    Usual Adult Dose for CMV Infection:

    400 mg orally twice a dayUse: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet

    Usual Pediatric Dose for CMV Infection:

    12 years or older:-At least 35 kg: 400 mg orally twice a dayUse: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet

    Warnings

    Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

    What other drugs will affect Maribavir

    Tell your doctor about all your other medicines, especially:

  • phenobarbital or other barbiturate medicine;
  • St. John's wort;
  • an antibiotic--rifabutin, rifampin; or
  • seizure medicine--carbamazepine, phenytoin.
  • This list is not complete and many other drugs may affect maribavir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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