Meropenem and vaborbactam

Generic name: Meropenem And Vaborbactam
Brand names: Vabomere
Dosage form: intravenous powder for injection (1 g-1 g)
Drug class: Carbapenems / beta-lactamase inhibitors

Usage of Meropenem and vaborbactam

Meropenem and vaborbactam are antibiotics that fight bacteria.

Meropenem and vaborbactam is a combination medicine used to treat serious urinary tract infections in adults.

Meropenem and vaborbactam may also be used for purposes not listed in this medication guide.

Meropenem and vaborbactam side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Meropenem and vaborbactam may cause serious side effects. Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;
  • a seizure (convulsions);
  • sores or white patches in your mouth or throat (yeast infection or "thrush");
  • severe tingling or numbness; or
  • unusual bleeding or bruising.

    • Common side effects of meropenem and vaborbactam may include:

  • headache;
  • diarrhea; or
  • swelling or irritation where the medicine was injected.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Meropenem and vaborbactam

    You may not be able to use this medicine if you have ever had an allergic reaction to any antibiotics, including:

  • meropenem or vaborbactam;
  • amoxicillin, ampicillin, Augmentin, Timentin, Unasyn, Zosyn;
  • dicloxacillin, nafcillin, oxacillin, ticarcillin; or
  • any penicillin antibiotic.

    • To make sure meropenem and vaborbactam is safe for you, tell your doctor if you have ever had:

  • an allergy to a cephalosporin antibiotic (Cephalexin, Cefdinir, Keflex, Omnicef, and others);
  • a head injury or brain tumor;
  • epilepsy or other seizure disorder; or
  • kidney disease (or if you are on dialysis).

    • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

    Meropenem and vaborbactam can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding.

    Relate drugs

    How to use Meropenem and vaborbactam

    Usual Adult Dose for Pyelonephritis:

    4 g IV every 8 hoursDuration of therapy: Up to 14 daysUse: For the treatment of patients with complicated urinary tract infections (including pyelonephritis) due to susceptible EscheriChia coli, Klebsiella pneumoniae, Enterobacter cloacae species complex

    Usual Adult Dose for Urinary Tract Infection:

    4 g IV every 8 hoursDuration of therapy: Up to 14 daysUse: For the treatment of patients with complicated urinary tract infections (including pyelonephritis) due to susceptible Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae species complex

    Warnings

    Before you receive meropenem and vaborbactam, tell your doctor if you have a history of allergies to any antibiotic medications.

    What other drugs will affect Meropenem and vaborbactam

    Tell your doctor about all your current medicines and any you start or stop using, especially:

  • divalproex sodium;
  • probenecid; or
  • valproic acid.

    • This list is not complete. Other drugs may interact with meropenem and vaborbactam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords