Methylergonovine oral and injection

Generic name: Methylergonovine (oral And Injection)
Brand names: Methergine
Drug class: Uterotonic agents

Usage of Methylergonovine oral and injection

Methylergonovine is used just after a baby is born, to help deliver the placenta (also called the "afterbirth"). It is also used to help control bleeding and to improve muscle tone in the uterus after childbirth.

Methylergonovine may also be used for purposes not listed in this medication guide.

Methylergonovine oral and injection side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Methylergonovine may cause serious side effects. Call your doctor at once if you have:

  • increased blood pressure (severe headache, blurred vision, pounding in your neck or ears);
  • chest pain, sweating, pounding heartbeats or fluttering in your chest;
  • a seizure;
  • numbness, tingling, or cold feeling in your fingers or toes;
  • a light-headed feeling, like you might pass out; or
  • sudden numbness or weakness on one side of the body, problems with vision or speech, pain or swelling in one leg.
  • Common side effects of methylergonovine may include:

  • increased blood pressure (severe headache, blurred vision, pounding in your neck or ears);
  • a seizure; or
  • headache.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Methylergonovine oral and injection

    You should not use methylergonovine if you are allergic to it, or if you have:

  • high blood pressure;
  • toxemia of pregnancy; or
  • if your baby has not yet been born.
  • Tell your doctor if you have ever had:

  • liver or kidney disease; or
  • risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease).
  • You should not use methylergonovine during your pregnancy. methylergonovine is to be used only after delivery of your baby.

    Do not breast-feed within 12 hours after using methylergonovine. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

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    How to use Methylergonovine oral and injection

    Usual Adult Dose for Postpartum Bleeding:

    Parenteral: 0.2 mg IM after delivery of the placenta or during the puerperium; may be repeated at intervals of 2 to 4 hours as requiredOrally: 0.2 mg orally 3 or 4 times a day for a maximum of 1 week during the puerperium Comments: -Under full obstetric supervision, this drug may be given parenterally during the second stage of labor following delivery of the anterior shoulder.-IV administration should be avoided unless administration is considered life-saving; IV dosing is the same as IM, give IV slowly over at least 60 secondsUses: -For routine management of uterine atony, hemorrhage and subinvolution of the uterus following delivery of the placenta. -For control of uterine hemorrhage in the second stage of labor following delivery of the anterior shoulder.

    Warnings

    You should not use methylergonovine during your pregnancy. This medication is to be used only after delivery of your baby.

    Do not breast-feed within 12 hours after using methylergonovine. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

    What other drugs will affect Methylergonovine oral and injection

    Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

    Tell your doctor about all your current medicines. Many drugs can affect methylergonovine, especially:

  • anesthetics--halothane and methoxyflurane; or
  • a beta blocker--atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others.
  • This list is not complete and many other drugs may affect methylergonovine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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