Micrainin

Generic name: Meprobamate And Aspirin

Usage of Micrainin

Meprobamate and aspirin combination is used to relieve pain, anxiety, and tension in certain disorders or diseases.

This medicine is available only with your doctor's prescription.

Micrainin side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Wheezing, shortness of breath, troubled breathing, or tightness in chest

Symptoms of overdose

Any loss of hearing

bloody urine

confusion (severe)

convulsions (seizures)

diarrhea (severe or continuing)

dizziness or lightheadedness (continuing)

drowsiness (severe)

fast or deep breathing

hallucinations (seeing, hearing, or feeling things that are not there)

headache (severe or continuing)

increased sweating

nausea or vomiting (continuing)

nervousness or excitement (severe)

ringing or buzzing in ears (continuing)

slow heartbeat

slurred speech

staggering

stomach pain (severe or continuing)

unexplained fever

unusual or uncontrolled flapping movements of the hands, especially in elderly patients

unusual thirst

vision problems

weakness (severe)

Symptoms of overdose in children

Changes in behavior

drowsiness or tiredness (severe)

fast or deep breathing

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Bloody or black, tarry stools

confusion

skin rash, hives, or itching

sore throat and fever

unusual bleeding or bruising

unusual excitement

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Drowsiness

heartburn or indigestion

nausea with or without vomiting

stomach pain (mild)

Less common

Blurred vision or change in near or distant vision

dizziness or lightheadedness

headache

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Clumsiness or unsteadiness

confusion

convulsions (seizures)

hallucinations (seeing, hearing, or feeling things that are not there)

increased dreaming

muscle twitching

nausea or vomiting

nervousness or restlessness

nightmares

trembling

trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Micrainin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Do not give a medicine containing aspirin to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing this with your child's doctor. This is very important because aspirin may cause a serious illness called Reye's syndrome in children or teenagers with fever caused by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin (contained in this combination medicine), especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the chance of side effects during treatment.

Geriatric

Elderly people may be especially sensitive to the effects of meprobamate and aspirin. This may increase the chance of side effects during treatment.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Abrocitinib

Defibrotide

Dichlorphenamide

Influenza Virus Vaccine, Live

Ketorolac

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose

Aceclofenac

Acemetacin

Acenocoumarol

Acetazolamide

Alclometasone

Aldosterone

Alfentanil

Alipogene Tiparvovec

Alprazolam

Alteplase, Recombinant

Amcinonide

Amikacin

Amiloride

Amineptine

Amitriptyline

Amitriptylinoxide

Amobarbital

Amoxapine

Amphotericin B

Amtolmetin Guacil

Anagrelide

Anisindione

Apixaban

Aprobarbital

Ardeparin

Argatroban

Bacitracin

Beclomethasone

Bemetizide

Bemiparin

Benazepril

Bendroflumethiazide

Benzhydrocodone

Benzthiazide

Betamethasone

Betrixaban

Bivalirudin

Brinzolamide

Bromazepam

Bromfenac

Bromopride

Budesonide

Bufexamac

Bumetanide

Buprenorphine

Butabarbital

Butalbital

Butorphanol

Calcium Oxybate

Cannabidiol

Cannabis

Caplacizumab-yhdp

Celecoxib

Certoparin

Cetirizine

Chloral Hydrate

Chlordiazepoxide

Chlorothiazide

Chlorpropamide

Chlorthalidone

Chlorzoxazone

Choline Salicylate

Ciclesonide

Cilostazol

Cisplatin

Citalopram

Clobazam

Clobetasol

Clobetasone

Clocortolone

Clomipramine

Clonazepam

Clonixin

Clopamide

Clopidogrel

Clorazepate

Codeine

Cortisone

Curcumin

Cyclopenthiazide

Cyclosporine

Cyclothiazide

Dabigatran Etexilate

Dalteparin

Danaparoid

Dantrolene

Daridorexant

Deflazacort

Desipramine

Desirudin

Desmopressin

Desonide

Desoximetasone

Desvenlafaxine

Dexamethasone

Dexibuprofen

Dexketoprofen

Dexmedetomidine

Diazepam

Diazoxide

Dibenzepin

Diclofenac

Dicumarol

Diflorasone

Diflucortolone

Diflunisal

Difluprednate

Digoxin

Dihydrocodeine

Dipyrone

Dorzolamide

Dothiepin

Doxepin

Doxylamine

Droxicam

Duloxetine

Edoxaban

Emtricitabine

Enalapril

Enalaprilat

Enoxaparin

Eplerenone

Eptifibatide

Escitalopram

Esketamine

Eslicarbazepine Acetate

Estazolam

Ethacrynic Acid

Ethchlorvynol

Etodolac

Etofenamate

Etoricoxib

Etozolin

Felbinac

Fenoprofen

Fentanyl

Fepradinol

Feprazone

Feverfew

Flibanserin

Floctafenine

Flucloronide

Fluconazole

Fludrocortisone

Flufenamic Acid

Flumethasone

Flunisolide

Flunitrazepam

Fluocinolone

Fluocinonide

Fluocortin

Fluocortolone

Fluorometholone

Fluoxetine

Flurandrenolide

Flurazepam

Flurbiprofen

Fluticasone

Fluvoxamine

Fondaparinux

Foscarnet

Fosinopril

Fosphenytoin

Fospropofol

Furosemide

Gabapentin

Gabapentin Enacarbil

Gentamicin

Ginkgo

Glimepiride

Glipizide

Glyburide

Gossypol

Halazepam

Halcinonide

Halobetasol

Heparin

Hydrochlorothiazide

Hydrocodone

Hydrocortisone

Hydroflumethiazide

Hydromorphone

Ibrutinib

Ibuprofen

Imipramine

Indapamide

Indomethacin

Inotersen

Kanamycin

Ketamine

Ketazolam

Ketoprofen

Lacosamide

Lemborexant

Lepirudin

Levocetirizine

Levomilnacipran

Levorphanol

Lisinopril

Lithium

Lofepramine

Lofexidine

Lorazepam

Lormetazepam

Lornoxicam

Loteprednol

Loxapine

Loxoprofen

Lumiracoxib

Macimorelin

Magnesium Oxybate

Meclizine

Meclofenamate

Medazepam

Medrysone

Mefenamic Acid

Melitracen

Meloxicam

Melphalan

Meperidine

Mephenesin

Mephobarbital

Metaxalone

Metformin

Methadone

Methazolamide

Methocarbamol

Methohexital

Methotrexate

Methyclothiazide

Methylprednisolone

Metoclopramide

Metolazone

Midazolam

Milnacipran

Moexipril

Mometasone

Morniflumate

Morphine

Morphine Sulfate Liposome

Nabumetone

Nadroparin

Nalbuphine

Naproxen

Nateglinide

Nefazodone

Neomycin

Nepafenac

Netilmicin

Nicorandil

Niflumic Acid

Nimesulide

Nimesulide Beta Cyclodextrin

Nitrazepam

Nortriptyline

Olanzapine

Opipramol

Oxaprozin

Oxazepam

Oxycodone

Oxymorphone

Oxyphenbutazone

Paramethasone

Parecoxib

Parnaparin

Paromomycin

Paroxetine

Pemetrexed

Pentazocine

Pentobarbital

Pentosan Polysulfate Sodium

Pentoxifylline

Periciazine

Perindopril

Phenindione

Phenobarbital

Phenprocoumon

Phenylbutazone

Phenytoin

Piketoprofen

Piracetam

Piretanide

Piroxicam

Plazomicin

Polythiazide

Potassium Citrate

Potassium Oxybate

Pranoprofen

Prasugrel

Prazepam

Prednicarbate

Prednisolone

Prednisone

Pregabalin

Primidone

Proglumetacin

Propofol

Propyphenazone

Proquazone

Protein C

Protriptyline

Quazepam

Quinapril

Quinethazone

Ramipril

Remifentanil

Remimazolam

Repaglinide

Reteplase, Recombinant

Reviparin

Rimexolone

Rivaroxaban

Rofecoxib

Ropeginterferon Alfa-2b-njft

Salicylic Acid

Salsalate

Scopolamine

Secobarbital

Selumetinib

Sertraline

Sodium Oxybate

Sodium Salicylate

Sparsentan

Spectinomycin

Spirapril

Spironolactone

Streptomycin

Sufentanil

Sulindac

Sulodexide

Tacrolimus

Tapentadol

Temazepam

Tenofovir Alafenamide

Tenofovir Disoproxil Fumarate

Tenoxicam

Thiopental

Tianeptine

Tiaprofenic Acid

Ticagrelor

Ticlopidine

Tinzaparin

Tirofiban

Tobramycin

Tolazamide

Tolbutamide

Tolfenamic Acid

Tolmetin

Topiramate

Torsemide

Tramadol

Trandolapril

Trazodone

Treprostinil

Triamcinolone

Triamterene

Triazolam

Trichlormethiazide

Trimipramine

Turmeric

Valdecoxib

Valproic Acid

Vancomycin

Varicella Virus Vaccine, Live

Venlafaxine

Vilazodone

Vortioxetine

Warfarin

Xipamide

Zolpidem

Zuranolone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acebutolol

Atenolol

Betaxolol

Bisoprolol

Carteolol

Carvedilol

Celiprolol

Delapril

Esmolol

Imidapril

Labetalol

Levobunolol

Metipranolol

Metoprolol

Nadolol

Nebivolol

Nitroglycerin

Oxprenolol

Penbutolol

Pindolol

Probenecid

Propranolol

Sotalol

Streptokinase

Tamarind

Temocapril

Tenecteplase

Timolol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

How to use Micrainin

Take this medicine with food or a full glass (8 ounces) of water to lessen stomach irritation.

Do not take this medicine if it has a strong vinegar-like odor. This odor means the aspirin in it is breaking down. If you have any questions about this, check with your health care professional.

Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much meprobamate is taken, it may become habit-forming. Also, taking too much aspirin may cause stomach problems or lead to medical problems because of an overdose.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Adults—Oral, 1 or 2 tablets three or four times a day, as needed.

Children up to 12 years of age: Use is not recommended.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Warnings

If you will be taking this medicine regularly for a long time:

Your doctor should check your progress at regular visits.

Check with your doctor at least every 4 months to make sure you need to continue taking this medicine.

If you will be taking this medicine in large doses or for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping completely.

Check the labels of all nonprescription (over-the-counter [OTC]) and prescription medicines you now take. If any contain aspirin or other salicylates (including bismuth subsalicylate [e.g., Pepto-Bismol]), be especially careful. Taking or using any of these medicines while taking this combination medicine containing aspirin may lead to overdose. If you have any questions about this, check with your health care professional.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.

Stomach problems may be more likely to occur if you drink alcoholic beverages while being treated with this medicine, especially if you are taking the medicine in high doses or for a long time. Check with your doctor if you have any questions about this.

Too much use of this medicine together with certain other medicines may increase the chance of stomach problems. Therefore, do not regularly take this medicine together with any of the following medicines, unless directed to do so by your medical doctor or dentist:

Acetaminophen (e.g., Tylenol)

Diclofenac (e.g., Voltaren)

Diflunisal (e.g., Dolobid)

Etodolac (e.g., Lodine)

Fenoprofen (e.g., Nalfon)

Floctafenine (e.g., Idarac)

Flurbiprofen (oral) (e.g., Ansaid)

Ibuprofen (e.g., Motrin)

Indomethacin (e.g., Indocin)

Ketoprofen (e.g., Orudis)

Ketorolac (e.g., Toradol)

Meclofenamate (e.g., Meclomen)

Mefenamic acid (e.g., Ponstel)

Naproxen (e.g., Naprosyn)

Phenylbutazone (e.g., Butazolidin)

Piroxicam (e.g., Feldene)

Sulindac (e.g., Clinoril)

Tiaprofenic acid (e.g., Surgam)

Tolmetin (e.g., Tolectin)

If you are taking a laxative containing cellulose, do not take it within 2 hours of taking this medicine. Taking these medicines close together may make this medicine less effective by preventing the aspirin (contained in this combination medicine) from being absorbed by your body.

For diabetic patients:

False urine sugar test results may occur if you take 8 or more 325-mg (5-grain) doses of aspirin (contained in this combination medicine) every day for several days in a row. Smaller doses or occasional use of aspirin usually will not affect urine sugar tests. If you have any questions about this, check with your doctor, especially if your diabetes is not well controlled.

Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests, such as the metyrapone test and the phentolamine test, may be affected by this medicine.

If you plan to have surgery, including dental surgery, do not take aspirin (contained in this combination medicine) for 5 days before the surgery, unless otherwise directed by your medical doctor or dentist. Taking aspirin during this time may cause bleeding problems.

If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Taking an overdose of this medicine or taking alcohol or other CNS depressants with it may lead to unconsciousness and possibly death. Some signs of an overdose are continuing ringing or buzzing in ears; any hearing loss; severe confusion, drowsiness, or weakness; shortness of breath or slow or troubled breathing; staggering; and slow heartbeat.

This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Meprobamate (contained in this combination medicine) may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

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