Migranal nasal

Generic name: Dihydroergotamine (nasal)
Drug class: Antimigraine agents

Usage of Migranal nasal

Migranal is used to treat migraine headaches with or without aura in adults. This medicine nasal will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Migranal should not be used to treat any headache that seems to be different from your usual migraine headaches.

Migranal may also be used for purposes not listed in this medication guide.

Migranal nasal side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Migranal may cause serious side effects. Call your doctor at once if you have:

numbness, cold feeling, or pale appearance of your fingers or toes;

sudden or severe stomach pain, weight loss, nausea, vomiting, constipation, bloody diarrhea, fever;

severe headache, blurred vision, pounding in your neck or ears;

burning sensation in the nose, mouth, throat, and altered sense of taste;

fast or slow heart rate;

swelling or itching;

signs of a blood clot--sudden numbness or weakness on one side of the body, chest pain, problems with vision or speech, pain or swelling in one leg; or

heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

Common side effects of Migranal may include:

pain, bruising, swelling, or irritation where the medicine was applied;

drowsiness;

dizziness;

nausea, vomiting, diarrhea;

runny nose;

altered sense of taste; or

sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Migranal nasal

You should not use Migranal if you are allergic to it or similar medicines (ergotamine, ergonovine, methylergonovine, and others), or if you have or have ever had:

heart disease, angina (chest pain), blood circulation problems, coronary artery disease (clogged arteries), or a heart attack or stroke;

uncontrolled high blood pressure;

a serious infection called sepsis;

vascular surgery;

narrowing of blood vessels in the legs, arms, stomach, or kidneys (peripheral vascular disease); or

severe liver or kidney disease.

Some drugs should not be used with Migranal. Your treatment plan may change if you also use:

medicines that raise your blood pressure or constrict your blood vessels;

an antibiotic such as troleandomycin, clarithromycin, or erythromycin;

antifungal medicine such as itraconazole or ketoconazole; or

antiviral medicine for HIV or hepatitis C.

Tell your doctor if you have ever had:

blood circulation problems in your arms, hands, legs, or feet;

chest pain, shortness of breath;

risk factors for coronary artery disease (high blood pressure, high cholesterol, diabetes, menopause, smoking, family history of coronary artery disease, being overweight, being over 40 and a man); or

liver or kidney disease.

Migranal may cause preterm labor. Tell your doctor if you are pregnant or plan to become pregnant. Do not use Migranal if you are pregnant.

Do not breastfeed while using this medicine, and for at least 3 days after your last dose.

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How to use Migranal nasal

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Migranal spray is absorbed quickly through your nasal passages and is for use only in the nose. The nasal spray liquid should not be injected into the body.

Your first dose may be given in a medical setting where any serious side effects can be quickly treated.

You should use Migranal as soon as your headache begins, but it may be given at any time during the migraine episode.

Before your first use, prime the nasal spray device with 4 sprays into the air, away from your face.

Trudhesa: apply one spray in each nostril then another spray in each nostril 1 hour later only if your headache comes back or if you only get some relief from your headache. Use a new nasal spray device for the second dose.

Migranal: apply one spray in each nostril followed by another spray in each nostril 15 minutes later, for a total of 4 sprays.

You may need medical tests to check your heart function.

The nasal spray vial should be thrown away 8 hours after it has been opened.

Store at room temperature away from moisture, heat, and light. Do not keep this medicine in a refrigerator and do not freeze.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with Migranal.

What other drugs will affect Migranal nasal

Tell your doctor about all your current medicines. Many drugs can affect Migranal, especially:

heart or blood pressure medication;

nicotine gum or patches;

an antidepressant; or

medicine to treat asthma.

This list is not complete and many other drugs may affect Migranal. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.