Mirabegron

Generic name: Mirabegron
Drug class: Urinary antispasmodics

Usage of Mirabegron

Mirabegron is used in adults to treat overactive bladder with symptoms of frequent or urgent urination and urinary incontinence. Mirabegron is sometimes used together with another medicine called solifenacin (Vesicare).

Mirabegron is used in children to treat neurogenic detrusor overactivity (NDO). Urinary incontinence caused by NDO is related to permanent nerve damage from conditions such as multiple sclerosis or spinal injury.

Mirabegron tablets may be used in children at least 3 years old. Mirabegron granules are for use in children at least 3 years old who also weigh at least 77 pounds (35 kilograms).

Mirabegron may also be used for purposes not listed in this medication guide.

Mirabegron side effects

Stop using mirabegron and get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mirabegron may cause serious side effects. Call your doctor at once if you have:

pain or burning when you urinate; or

dangerously high blood pressure--severe headache, blurred vision, pounding in your neck or ears.

Common side effects of mirabegron may include:

painful urination;

increased blood pressure;

sinus pain, sore throat;

constipation;

headache; or

dry mouth or fast heartbeats (when taken with solifenacin).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Mirabegron

You should not use mirabegron if you are allergic to it.

Tell your doctor if you have ever had:

high blood pressure;

a bladder obstruction;

trouble emptying your bladder (very little urine or a weak stream of urine);

kidney disease; or

liver disease.

Tell your doctor if you are pregnant or breastfeeding.

Mirabegron should not be given to a child younger than 3 years old.

Relate drugs

How to use Mirabegron

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

If you take mirabegron with solifenacin, take both medicines at the same time each day.

Take the mirabegron tablet with a full glass of water. Swallow the tablet whole and do not crush, chew, or break it.

An adult may take a mirabegron tablet with or without food. However, a child should take the tablet with food.

Both adults and children should take mirabegron granules with food.

A pharmacist will mix mirabegron granules into a suspension (liquid) before you receive the medicine.

Shake the suspension before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

If the suspension will not be used for 2 days or longer, shake the bottle vigorously for 1 minute each day to keep the granules thoroughly mixed.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Your dose needs may change if you switch from using mirabegron tablets to using the suspension. Avoid medication errors by using only the form and strength your doctor prescribes.

Your blood pressure will need to be checked often.

It may take up to 8 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat. Throw away any unused mirabegron suspension after the expiration date on the medicine label has passed.

Warnings

You should not use mirabegron if you have uncontrolled hypertension (high blood pressure).

What other drugs will affect Mirabegron

Tell your doctor about all your other medicines, especially:

digoxin;

flecainide;

propafenone;

solifenacin; or

thioridazine.

This list is not complete. Other drugs may affect mirabegron, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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