Mitapivat

Generic name: Mitapivat
Dosage form: oral tablet (20 mg; 20 mg-5 mg; 5 mg; 50 mg; 50 mg-20 mg)
Drug class: Miscellaneous metabolic agents

Usage of Mitapivat

Mitapivat is used to treat low red blood cell counts caused by hemolytic anemia (early breakdown of red blood cells) in adults with pyruvate kinase deficiency.

Mitapivat may also be used for purposes not listed in this medication guide.

Mitapivat side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mitapivat may cause serious side effects. Call your doctor at once if you have:

  • jaundice (yellowing of the skin or eyes);
  • dark urine;
  • dizziness;
  • confusion;
  • tiredness; or
  • shortness of breath.
  • Common side effects of mitapivat may include:

  • flushing (sudden warmth, redness, or tingly feeling);
  • breast swelling and tenderness;
  • changes in sexual function;
  • irregular heart rhythm;
  • abnormal blood tests; or
  • back or joint pain.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Mitapivat

    Tell your doctor if you have ever had:

  • liver disease.
  • Tell your doctor if you are pregnant or breastfeeding.

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    How to use Mitapivat

    Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

    You may take mitapivat with or without food.

    Swallow the tablet whole and do not crush, chew, or break it.

    Do not share mitapivat with another person, even if they have the same symptoms you have.

    Do not change your dose or stop using mitapivat without talking to your doctor. Your doctor will give you instructions for stopping mitapivat.

    Store this medicine in the original container at room temperature.

    Warnings

    Call your doctor at once if you have jaundice (yellowing of the skin or eyes), dark urine, dizziness, confusion, tiredness, or shortness of breath.

    What other drugs will affect Mitapivat

    Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

    Other drugs may affect mitapivat, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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