Molindone

Generic name: Molindone
Brand names: Moban
Dosage form: oral tablet (10 mg; 25 mg; 5 mg)
Drug class: Miscellaneous antipsychotic agents

Usage of Molindone

Molindone is an antipsychotic medicine that is used to treat schizophrenia.

Molindone may also be used for purposes not listed in this medication guide.

Molindone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

High doses or long-term use of molindone can cause a serious movement disorder that may not be reversible. The longer you use molindone, the more likely you are to develop this disorder, especially if you are a woman or an older adult.

Molindone may cause serious side effects. Call your doctor at once if you have:

  • any new or unusual muscle movements you cannot control;
  • tremor (uncontrolled shaking);
  • trouble breathing or swallowing;
  • a seizure (convulsions);
  • (in women) irregular menstrual periods, breast or vaginal changes, nipple discharge;
  • (in men) breast swelling, impotence;
  • severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; or
  • low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing.
  • Common side effects of molindone may include:

  • drowsiness;
  • fast heart rate, feeling restless or nevous, being unable to sit still;
  • blurred vision;
  • dry mouth;
  • little or no urination;
  • nausea, constipation;
  • breast swelling or discharge;
  • impotence, sexual problems; or
  • changes in your menstrual periods.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Molindone

    You should not use molindone if you are allergic to it, or:

  • if you have decreased alertness caused by taking certain medications or drinking alcohol.
  • Molindone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

    Tell your doctor if you have ever had:

  • epilepsy or other seizure disorder;
  • low white blood cell (WBC) counts;
  • urination problems; or
  • breast cancer.
  • Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking molindone without your doctor's advice.

    It is not known whether molindone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

    It may not be safe to breastfeed while using molindone. Ask your doctor about any risk.

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    How to use Molindone

    Usual Adult Dose for Schizophrenia:

    Initial Dosing Schedule:-Recommended dose: 50 to 75 mg orally per day, increasing the dose to 100 mg/day in 3 to 4 days-Maximum dose: 225 mg/dayMaintenance Dosing Schedule:-Mild symptomology: 5 to 15 mg orally 3 to 4 times a day-Moderate symptomology: 10 to 25 mg orally 3 to 4 times a day-Severe symptomology: Up to 225 mg/dayComments:-Patients with severe symptomology may require 225 mg/day.-Elderly and/or debilitates patients should begin on the lower dosage.Use: Management of schizophrenia

    Usual Pediatric Dose for Schizophrenia:

    12 to 18 years:Initial Dosage Schedule:-Recommended dose: 50 to 75 mg orally per day, increasing the dose to 100 mg/day in 3 to 4 days-Maximum dose: 225 mg/dayMaintenance Dosing Schedule:-Mild symptomology: 5 to 15 mg orally 3 to 4 times a day-Moderate symptomology: 10 to 25 mg orally 3 to 4 times a day-Severe symptomology: Up to 225 mg/dayComments:-Patients with severe symptomology may require 225 mg/day.-Debilitated patients should begin on the lower dosage.Use: Management of schizophrenia

    Warnings

    You should not use molindone if you have decreased alertness caused by taking certain medications or drinking alcohol.

    Molindone is not approved for use in older adults with dementia-related psychosis.

    What other drugs will affect Molindone

    Taking molindone with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Tell your doctor about all your other medicines, especially:

  • phenytoin; or
  • an antibiotic such as demeclocycline, doxycycline, minocycline, or tetracycline.
  • This list is not complete. Other drugs may affect molindone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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