Mycamine

Generic name: Micafungin
Drug class: Echinocandins

Usage of Mycamine

Mycamine is an antifungal medication that fights infections caused by fungus.

Mycamine is used to treat infections caused by the Candida fungus. It is also used to prevent Candida fungal infections in stem cell transplant patients. Mycamine is for use in adults and pediatric patients.

Mycamine may also be used for purposes not listed in this medication guide.

Mycamine side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Mycamine: hives; difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

pale or yellowed skin, dark colored urine, fever, confusion or weakness;

swelling, rapid weight gain, little or no urinating; or

upper stomach pain, itching, loss of appetite, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common Mycamine side effects may include:

nausea, vomiting, diarrhea;

flushing (warmth, redness, or tingly feeling); or

mild itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Mycamine

You should not use Mycamine if you are allergic to micafungin or similar medicines such as caspofungin (Cancidas) or anidulafungin (Eraxis).

To make sure you can safely use Mycamine, tell your doctor if you have any of these other conditions:

liver disease; or

kidney disease.

FDA pregnancy category C. It is not known whether Mycamine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether micafungin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Relate drugs

How to use Mycamine

Usual Adult Dose for Esophageal Candidiasis:

150 mg via IV infusion once a day Duration of therapy: Has ranged from 10 to 30 days (mean duration: 15 days)

Usual Adult Dose for Fungal Infection Prophylaxis:

50 mg via IV infusion once a day Duration of therapy: Has ranged from 6 to 51 days (mean duration: 19 days) Comments: -Efficacy against infections due to fungi other than Candida has not been established. Approved indication: Prophylaxis of Candida infections in hematopoietic stem cell transplant recipients

Usual Adult Dose for Candidemia:

100 mg via IV infusion once a day Duration of therapy: Has ranged from 10 to 47 days (mean duration: 15 days) Comments: -Not adequately studied in patients with endocarditis, osteomyelitis, and meningitis due to Candida infections. Approved indications: Treatment of patients with candidemia, acute disseminated candidiasis, Candida peritonitis and abscesses

Usual Pediatric Dose for Esophageal Candidiasis:

4 months or older: 30 kg or less: 3 mg/kg via IV infusion once a day Greater than 30 kg: 2.5 mg/kg via IV infusion once a day Maximum dose: 150 mg per day

Usual Pediatric Dose for Fungal Infection Prophylaxis:

4 months or older: 1 mg/kg via IV infusion once a day Maximum dose: 50 mg per day Comments: -Efficacy against infections due to fungi other than Candida has not been established. Approved indication: Prophylaxis of Candida infections in hematopoietic stem cell transplant recipients

Usual Pediatric Dose for Candidemia:

4 months or older: 2 mg/kg via IV infusion once a day Maximum dose: 100 mg per day Comments: -Not adequately studied in patients with endocarditis, osteomyelitis, and meningitis due to Candida infections. Approved indications: Treatment of patients with candidemia, acute disseminated candidiasis, Candida peritonitis and abscesses

Warnings

You should not use Mycamine if you are allergic to micafungin or similar medicines such as caspofungin (Cancidas) or anidulafungin (Eraxis).

Before using Mycamine, tell your doctor if you are allergic to any drugs, if you have liver or kidney disease, or if you are also using sirolimus (Rapamune), itraconazole (Sporanox), or nifedipine (Adalat, Procardia).

Mycamine is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

What other drugs will affect Mycamine

Other drugs may interact with Mycamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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