Mycophenolic acid
Generic name: Mycophenolic Acid
Brand names: Myfortic
Dosage form: oral delayed release tablet (180 mg; 360 mg)
Drug class:
Selective immunosuppressants
Usage of Mycophenolic acid
Mycophenolic acid is used with other medicines to prevent organ rejection after a kidney transplant. mycophenolic acid is for use in adults and children at least 5 years old.
Mycophenolic acid may also be used for purposes not listed in this medication guide.
Mycophenolic acid side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Mycophenolic acid may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Mycophenolic acid affects your immune system and may increase your risk of cancer or serious infection. Call your doctor right away if you have:
Also call your doctor at once if you have:
Common side effects of mycophenolic acid may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Mycophenolic acid
You should not use this medicine if you are allergic to mycophenolic acid, mycophenolate mofetil, or mycophenolate sodium.
Talk with your doctor about the risks and benefits of mycophenolic acid. This medicine can affect your immune system, which may increase your risk of cancer, serious or fatal infections, or kidney transplant failure.
Tell your doctor if you have ever had:
This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolic acid, and for at least 6 weeks after your last dose.
Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose.
Mycophenolic acid can make birth control pills less effective. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy.
You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy.
This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions.
If a pregnancy occurs during treatment, do not stop taking mycophenolic acid. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191).
Mycophenolic acid is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are unable to use other needed transplant medications.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
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How to use Mycophenolic acid
Usual Adult Dose for Organ Transplant -- Rejection Prophylaxis:
720 mg orally 2 times dailyComments:-This drug should be used in combination with cyclosporine and corticosteroids.-Take on an empty stomach 1 hour before or 2 hours after food.-Swallow tablets whole; do not crush, chew, or divide.Use: For prophylaxis of organ rejection in kidney transplant
Usual Pediatric Dose for Organ Transplant -- Rejection Prophylaxis:
5 years and older:-In conversion (at least 6 months posttransplant): 400 mg/m2 orally 2 times a day (up to a maximum dose of 720 mg 2 times a day)Note: Pediatric patients with a BSA of 1.19 to 1.58 m2 may be dosed either with three of the 180 mg tablets, or one 180 mg tablet plus one 360 mg tablet 2 times a day. Patients with a BSA greater than 1.58 m2 may be dosed either with four of the 180 mg tablets, or two of the 360 mg tablets twice daily. Pediatric doses for patients with BSA less than 1.19 m2 cannot be accurately administered using currently available formulations of this drug.Comments:-This drug should be used in combination with cyclosporine and corticosteroids.-Take on an empty stomach 1 hour before or 2 hours after food.-Swallow tablets whole; do not crush, chew, or divide.Use: For the prophylaxis of organ rejection in pediatric patients 5 years of age and older who are at least 6 months post kidney transplant
Warnings
mycophenolic acid can cause a miscarriage or birth defects when used during pregnancy. Both men and women should use effective birth control to prevent pregnancy during and shortly after treatment with mycophenolic acid.
Using mycophenolic acid may increase your risk of cancer, serious infections, or kidney transplant failure.
Call your doctor right away if you have symptoms such as: fever, swollen glands, weight loss, vomiting or diarrhea, painful urination, a new skin lesion, any change in your mental state, weakness on one side of your body, or pain near your transplanted kidney.
What other drugs will affect Mycophenolic acid
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect mycophenolic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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