Mydcombi

Generic name: Phenylephrine Hydrochloride And Tropicamide
Dosage form: Ophthalmic Spray
Drug class: Mydriatics

Usage of Mydcombi

Mydcombi is a combination eye spray that contains phenylephrine hydrochloride and tropicamide and may be used to dilate the pupils before an eye examination or when short-term pupil dilation is required.

Mydcombi contains two common medications routinely used for pupil dilation before a comprehensive eye examination. It uses the Optejet dispenser which allows the medication to be delivered horizontally in microdroplets while standing or sitting, unlike traditional eye droppers that rely on gravity, and require a person to have their head tilted back or lying down.

Mydcombi side effects

Common side effects of Mydcombi include temporarily blurred vision and eyesight, sensitivity to light, disturbances to the cells on the surface of the eye (superficial punctate keratitis), and mild eye discomfort. Increased pressure within the eye (intraocular pressure) has been reported following the use of mydriatics.

Common systemic adverse reactions may include mouth dryness, tachycardia, headache, allergic reactions, nausea, vomiting, pallor, central nervous system disturbances, and muscle rigidity.

You may experience sensitivity to light and blurred vision while your pupils are dilated.

Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Before taking Mydcombi

There are no human or animal data regarding the use of Mydcombi during pregnancy. It should only be used if the potential benefits outweigh the potential risk to the unborn child.

There are no data for the use of Mydcombi during breastfeeding.

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How to use Mydcombi

Adults and children over the age of 1 year: Administer one metered spray to the cornea of each eye to be dilated, and repeat after 5 minutes.

Children younger than 1 year of age: Administer one metered spray to the cornea of each eye to be dilated, up to a maximum of 3 sprays per eye per day.

The Optejet® dispenser uses high-precision piezo-print technology to deliver 0.008 mL of solution, which is less than 20% of that delivered using conventional eyedroppers, thus reducing overdosing and exposure to drugs and preservatives. The solution is dispensed to the ocular surface in approximately 80 milliseconds, which is faster than the ocular blink reflex.

Warnings

Mydcombi is not for injection and is only for topical use in the eye.

Other warnings and precautions associated with Mydcombi include:

Rarely, significant elevations in blood pressure may occur. Be cautious when using in children less than 5 years of age, and in patients with cardiovascular disease or hyperthyroidism. Blood pressure should be monitored post-treatment

Rare incidences of central nervous system disturbances have been reported in children

May produce a transient increase in intraocular pressure

Rebound Miosis (small or constricted pupils) has been reported 1 day after administration.

What other drugs will affect Mydcombi

Mydcombi may interact with:

Atropine-like medications: May exaggerate the adrenergic pressor response

Cholinergic agonists and ophthalmic cholinesterase inhibitors: may interfere with the antihypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors

Potent inhalation anesthetic agents: These may potentiate the cardiovascular depressant effects of these agents.

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