Nifurtimox

Generic name: Nifurtimox
Brand names: Lampit
Dosage form: oral tablet (120 mg; 30 mg)
Drug class: Miscellaneous antibiotics

Usage of Nifurtimox

Nifurtimox is used to treat Chagas disease, a condition caused by a parasite. Chagas disease occurs most commonly in Mexico, Central America, and South America.

Nifurtimox is for use in children from birth through their 17th year. A child must weigh at least 5.5 pounds (2.5 kilograms) before taking nifurtimox.

Nifurtimox may also be used for purposes not listed in this medication guide.

Nifurtimox side effects

Get emergency medical help if the child has signs of an allergic reaction: hives, itching; feeling light-headed; difficult breathing; swelling of the face, lips, tongue, or throat.

Call your child's doctor at once if the child has:

  • a decreased appetite and weight loss;
  • new or worsening symptoms of a pre-existing condition (such as a brain injury, seizures, behavior changes, or mental health problems); or
  • worsening symptoms of porphyria (dark urine, severe stomach pain, muscle pain, numbness, tingling, mental changes, or skin sensitivity to light).
  • Common side effects of nifurtimox may include:

  • stomach pain, nausea, vomiting;
  • loss of appetite;
  • fever;
  • rash; or
  • headache.
  • This is not a complete list of side effects and others may occur. Call your child's doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Nifurtimox

    Nifurtimox should not be used if the child is allergic to it.

    Tell your child's doctor if the child has ever had:

  • a brain injury;
  • a seizure;
  • mental illness or psychosis;
  • kidney disease (or if the child is on dialysis);
  • liver disease; or
  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
  • Nifurtimox can harm an unborn baby if the mother or the father is using this medicine.

  • If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 6 months after your last dose.
  • If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
  • Tell the doctor right away if a pregnancy occurs.
  • It may be harder for you to get a woman pregnant while you are using this medicine.

    If you are breastfeeding, tell the doctor if you notice symptoms in the nursing baby such as fussiness, decreased appetite, vomiting, rash, or fever.

    Relate drugs

    How to use Nifurtimox

    Usual Pediatric Dose for Trypanosomiasis:

    BIRTH (TERM NEONATE) TO LESS THAN 18 YEARS:Total Daily Dosage Based on Body Weight:-Weight 2.5 to less than 40 kg: 10 to 20 mg/kg/day orally in divided doses 3 times a day-Weight at least 40 kg: 8 to 10 mg/kg/day orally in divided doses 3 times a dayIndividual Dosages Based on Body Weight:-Weight 2.5 to 4.5 kg: 15 mg orally 3 times a day-Weight 4.6 to less than 9 kg: 30 mg orally 3 times a day-Weight 9 to less than 13 kg: 45 mg orally 3 times a day-Weight 13 to less than 18 kg: 60 mg orally 3 times a day-Weight 18 to less than 22 kg: 75 mg orally 3 times a day-Weight 22 to less than 27 kg: 90 mg orally 3 times a day-Weight 27 to less than 35 kg: 120 mg orally 3 times a day-Weight 35 to less than 41 kg: 180 mg orally 3 times a day-Weight 41 to less than 51 kg: 120 mg orally 3 times a day-Weight 51 to less than 71 kg: 180 mg orally 3 times a day-Weight 71 to less than 91 kg: 240 mg orally 3 times a day-Weight at least 91 kg: 300 mg orally 3 times a dayDuration of Therapy: 60 daysComments:-During therapy, patients can lose their appetite or have nausea/vomiting which can lead to weight loss; body weight should be checked every 14 days and dose should be adjusted accordingly.Use: For the treatment of Chagas disease (American trypanosomiasis) due to Trypanosoma cruzi

    Warnings

    Follow all directions on your medicine label and package. Tell each of your child's healthcare providers about all the medical conditions, allergies, and medicines the child uses.

    Do not drink alcohol while taking nifurtimox.

    What other drugs will affect Nifurtimox

    Other drugs may affect nifurtimox, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell the doctor about all other medicines your child use.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords