Nitroprusside

Generic name: Nitroprusside
Dosage form: intravenous solution (20 mg/100 mL-NaCl 0.9%; 25 mg/mL)

Usage of Nitroprusside

Nitroprusside is a vasodilator that is used to treat congestive heart failure and life-threatening high blood pressure (hypertensive crisis).

Nitroprusside is also used to control blood pressure during a surgery.

Nitroprusside may also be used for purposes other than those listed in this medication guide.

Nitroprusside side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • a light-headed feeling, even while lying down;
  • chest pain, severe shortness or breath;
  • pounding heartbeats, sweating;
  • a restless or uneasy feeling, or if you feel very weak or tired;
  • stomach pain, nausea, vomiting;
  • headache, confusion, ringing in your ears;
  • muscle pain or twitching, problems with muscle movement;
  • a numb or cold feeling in your arms and legs; or
  • blue colored lips, fingers, or toes.
  • Common side effects of nitroprusside may include:

  • flushing (sudden warmth, redness, or tingly feeling); or
  • bruising or irritation around the IV needle.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Nitroprusside

    You should not be treated with nitroprusside if you are allergic to it, or if you have:

  • hereditary vision loss (Leber's disease);
  • vision problems caused by smoking; or
  • a history of blood clot in your brain.
  • If possible during an emergency, tell your caregivers if you've ever had:

  • heart failure, heart attack, or stroke;
  • low blood pressure;
  • blood circulation problems in your arms or legs;
  • liver disease;
  • anemia (low red blood cells);
  • sepsis (a severe reaction to an infection); or
  • a head injury, brain tumor, or other cause of increased pressure inside the skull.
  • If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

    How to use Nitroprusside

    Nitroprusside is injected into a vein through an infusion pump. A healthcare provider will give you this injection in a medical setting.

    For hypertensive crisis, nitroprusside is usually given only until you are able to take a longer-acting medicine to lower your blood pressure.

    Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.

    Your blood will also be tested to make sure nitroprusside is not causing harmful effects.

    Warnings

    Nitroprusside is given by a healthcare provider. Your vital signs will be watched closely while you are receiving nitroprusside.

    What other drugs will affect Nitroprusside

    Tell your doctor if you take any type of blood pressure medication.

    Other drugs may affect nitroprusside, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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