Nizatidine

Generic name: Nizatidine
Drug class: H2 antagonists

Usage of Nizatidine

Nizatidine is a histamine-2 blocker that works by decreasing the amount of acid produced by the stomach.

Nizatidine is used to treat ulcers in the stomach and intestines. Nizatidine also treats heartburn and erosive esophagitis caused by gastroesophageal reflux disease (GERD), a condition in which acid backs up from the stomach into the esophagus.

Nizatidine may also be used for purposes not listed in this medication guide.

Nizatidine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Nizatidine may cause serious side effects. Stop using nizatidine and call your doctor at once if you have:

worsening heartburn;

chest pain;

pale skin, feeling light-headed or short of breath; or

jaundice (yellowing of the skin or eyes).

Common side effects of nizatidine may include:

headache, dizziness;

diarrhea; or

runny or stuffy nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Nizatidine

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

You should not use nizatidine if you are allergic to nizatidine or similar stomach medicines such as ranitidine (Zantac), cimetidine (Tagamet), or famotidine (Pepcid).

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

pain when swallowing food;

bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

heartburn that has lasted for longer than 3 months;

heartburn that causes you to wheeze or feel like you might pass out;

unusual weight loss;

stomach pain, nausea, or vomiting;

frequent chest pain;

kidney disease; or

liver disease.

It is not known whether nizatidine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Nizatidine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking this medication.

Do not give this medication to a child younger than 12 years old without the advice of a doctor.

Relate drugs

How to use Nizatidine

Usual Adult Dose for Duodenal Ulcer:

300 mg orally once a day at bedtime OR 150 mg orally 2 times a dayDuration of therapy: Up to 8 weeksComment: Most patients heal within 4 weeks.Use: Treatment of active duodenal ulcer

Usual Adult Dose for Duodenal Ulcer Prophylaxis:

150 mg orally once a day at bedtimeDuration of therapy: Up to 1 yearComment: Efficacy and safety data for the maintenance treatment of duodenal ulcer beyond 1 year are unknown.Use: Maintenance therapy for duodenal ulcer patients after healing of an active duodenal ulcer

Usual Adult Dose for Gastric Ulcer:

300 mg orally once a day at bedtime OR 150 mg orally 2 times a dayDuration of therapy: Up to 12 weeksComment: Malignant gastric ulceration should be excluded prior to starting treatment.Use: Treatment of active benign gastric ulcer

Usual Adult Dose for Erosive Esophagitis:

150 mg orally 2 times a dayDuration of therapy: Up to 12 weeksUse: Treatment of endoscopically diagnosed esophagitis (including erosive and ulcerative esophagitis) and associated heartburn due to gastroesophageal reflux disease (GERD)

Usual Adult Dose for Gastroesophageal Reflux Disease:

Usual Pediatric Dose for Erosive Esophagitis:

12 years and older: 150 mg orally 2 times a day-Maximum dose: 300 mg/day-Duration of therapy: Up to 8 weeksUse: Treatment of endoscopically diagnosed esophagitis (including erosive and ulcerative esophagitis) and associated heartburn due to GERD

Usual Pediatric Dose for Gastroesophageal Reflux Disease:

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Nizatidine

Other drugs may interact with nizatidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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