Norflex (Orphenadrine Injection)

Generic name: Orphenadrine
Drug class: Skeletal muscle relaxants

Usage of Norflex (Orphenadrine Injection)

Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem .

Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects .

This medicine is available only with your doctor's prescription .

Norflex (Orphenadrine Injection) side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

Cough

difficulty swallowing

dizziness

fast heartbeat

hives

itching

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

shortness of breath

skin rash

tightness in chest

unusual tiredness or weakness

wheezing

Incidence not known

Abdominal or stomach pain

diarrhea

fast, pounding, or irregular heartbeat or pulse

fever

glaucoma

joint or muscle pain

nausea

numbness or tingling of face, hands, or feet

redness and soreness of eyes

shortness of breath

sores in mouth

swelling of feet or lower legs

vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of Overdose

Blurred vision

confusion, delirium, or hallucinations

constipation

difficult urination

drowsiness

dry eyes, mouth, nose, or throat

eye pain

flushing or redness of face

troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Anxiety

deep or fast breathing with dizziness

headache

irritability

itching skin

mental confusion

nervousness

numbness of feet, hands and around mouth

restlessness

trembling or shaking of hands or feet shakiness in legs, arms, hands, or feet

unusually large pupils of eyes

weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Norflex (Orphenadrine Injection)

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of orphenadrine in the pediatric population. Safety and efficacy have not been established .

Geriatric

No information is available on the relationship of age to the effects of orphenadrine in geriatric patients. However, elderly patients are more likely to have age-related heart, liver, or kidney problems which may require caution in patients receiving orphenadrine .

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Potassium Citrate

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alfentanil

Alprazolam

Amantadine

Amifampridine

Benzhydrocodone

Bromazepam

Buprenorphine

Butorphanol

Calcium Oxybate

Cannabidiol

Cannabis

Cetirizine

Clobazam

Clonazepam

Clozapine

Codeine

Daridorexant

Dexmedetomidine

Dihydrocodeine

Donepezil

Doxylamine

Esketamine

Fentanyl

Flibanserin

Gabapentin

Gabapentin Enacarbil

Glucagon

Glycopyrrolate

Glycopyrronium Tosylate

Hydrocodone

Hydromorphone

Ketamine

Lacosamide

Lemborexant

Levocetirizine

Levorphanol

Lofexidine

Loxapine

Magnesium Oxybate

Meperidine

Methacholine

Methadone

Metoclopramide

Midazolam

Morphine

Morphine Sulfate Liposome

Nalbuphine

Olanzapine

Oxycodone

Oxymorphone

Pentazocine

Phenobarbital

Potassium Oxybate

Pregabalin

Primidone

Quetiapine

Remifentanil

Remimazolam

Revefenacin

Ropeginterferon Alfa-2b-njft

Scopolamine

Secretin Human

Sodium Oxybate

Sufentanil

Tapentadol

Tiotropium

Topiramate

Tramadol

Trazodone

Zolpidem

Zuranolone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Perphenazine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Relate drugs

How to use Norflex (Orphenadrine Injection)

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins or into your muscle .

Warnings

Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.