Nourianz

Generic name: Istradefylline
Drug class: Miscellaneous antiparkinson agents

Usage of Nourianz

Nourianz is is an adenosine receptor antagonist. Adenosine receptors are involved with the regulation of motor (muscle) behaviour.

Nourianz is given with levodopa and Carbidopa to treat "wearing-off" episodes (muscle stiffness, loss of muscle control) in people with Parkinson's disease.

Nourianz is a prescription medicine and is supplied as a 20mg or 40mg tablet.

Nourianz side effects

Get emergency medical help if you have signs of an allergic reaction to Nourianz: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

uncontrolled or involuntary muscle movements;

unusual thoughts or behavior;

confusion, hallucinations; or

risk-taking behavior, being impulsive.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

Common Nourianz side effects may include:

involuntary muscle movements;

hallucinations;

dizziness;

nausea, constipation; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Nourianz

To make sure Nourianz is safe for you, tell your doctor if you have ever had:

abnormal muscle movements;

mental illness or psychosis;

liver disease; or

if you smoke.

Tell your doctor if you are pregnant or breastfeeding.

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How to use Nourianz

Usual Adult Dose for Parkinson's Disease:

Initial dose: 20 mg orally once a day -Dose may be increased based on individual need and tolerability Maintenance dose: 20 to 40 mg orally once a day Maximum dose: 40 mg/day Use: As adjunctive treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing OFF episodes.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Nourianz

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may interact with istradefylline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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