NuvaRing

Generic name: Ethinyl Estradiol And Etonogestrel (vaginal Ring)
Drug class: Contraceptives

Usage of NuvaRing

The NuvaRing vaginal ring contains a combination of ethinyl estradiol and etonogestrel are female hormones that prevent ovulation (the release of an egg from an ovary).

The hormones in NuvaRing also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

The NuvaRing vaginal ring is used as contraception to prevent pregnancy.

NuvaRing side effects

Get emergency medical help if you have signs of an allergic reaction to NuvaRing: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Nuvaring may cause serious side effects. Stop using Nuvaring and call your doctor at once if you have:

signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;

signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;

heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;

toxic shock syndrome - sudden fever, body aches, skin rash, vomiting, diarrhea, and feeling dizzy or light-headed;

symptoms of depression - mood changes, thoughts about hurting yourself; or

liver problems - loss of appetite, upper stomach pain, tiredness, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects of NuvaRing may include:

headache;

mood changes;

decreased sex drive;

vaginal irritation or discharge, pain in your cervix;

menstrual cramps, breast pain or tenderness;

nausea, vomiting, stomach pain;

acne;

weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking NuvaRing

Using Nuvaring can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of using NuvaRing, or when you insert a new ring after not wearing one for 4 weeks or longer.

You should not use NuvaRing if you have:

untreated or uncontrolled high blood pressure;

heart disease (coronary artery disease, a heart valve disorder, history of heart attack, stroke, or blood clot);

an increased risk of having blood clots due to a heart problem or a hereditary blood disorder;

circulation problems (especially if caused by diabetes);

a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;

unusual vaginal bleeding that has not been checked by a doctor;

severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;

liver disease or liver cancer;

if you smoke and are over 35 years old; or

if you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Technivie).

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not use the vaginal ring if you smoke and are older than 35 years of age.

Do not use a vaginal ring if you are pregnant, or if you had a baby within the past 4 weeks. Remove the vaginal ring and call your doctor if you become pregnant, or if you miss two menstrual periods in a row.

To make sure NuvaRing is safe for you, tell your doctor if you have ever had:

heart disease, high blood pressure, or if you are prone to having blood clots;

high cholesterol or triglycerides (a type of fat in the blood);

liver or kidney disease;

depression;

diabetes, underactive thyroid, gallbladder disease;

a seizure or migraine headaches;

irregular menstrual cycles, toxic shock syndrome, or easy vaginal irritation;

jaundice caused by pregnancy or birth control pills;

a family history of breast cancer;

fibrocystic breast disease, or an abnormal mammogram; or

if you have recently had a miscarriage or abortion.

Using this medicine can increase your risk of blood clots, stroke, or heart attack. This risk is highest during your first year of using the vaginal ring, or when you insert a new ring after not wearing one for 4 weeks or longer.

You should not breast-feed while using a NuvaRing vaginal ring.

Relate drugs

How to use NuvaRing

Usual Adult Dose of NuvaRing for Contraception:

Insert 1 ring into the vagina and leave in place continuously for 3 weeks, then remove for 1 week and insert a new ring 1 week after the last ring was removed Comments: During the 1 week ring-free period, withdrawal bleeding usually occurs. Use: For females of reproductive age to prevent pregnancy

Warnings

Do not use a NuvaRing if you are pregnant or if you have recently had a baby.

You should not use Nuvaring if you have: uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not use the NuvaRing vaginal ring if you smoke and are older than 35 years of age.

What other drugs will affect NuvaRing

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Some drugs can make birth control less effective, which may result in pregnancy. Use a barrier form of birth control (a male condom with spermicide, but not a diaphragm or female condom) with NuvaRing if you also use any of the following medicines:

aprepitant, bosentan, griseofulvin, St. John's wort;

efavirenz, nevirapine;

antiviral medicine to treat hepatitis C or HIV/AIDS - boceprevir, darunavir, darunavir/ritonavir, fosamprenavir, lopinavir, nelfinavir, ritonavir, telaprevir, tipranavir, lopinavir/ritonavir, tipranavir/ritonavir;

tuberculosis medicine - rifabutin, rifampin; or

seizure medicine - Carbamazepine, felbamate, oxcarbazepine, phenobarbital, phenytoin, rufinamide, topiramate.

Keep using the barrier birth control for at least 28 days after your last dose of any of these medicines.

This list is not complete and many other drugs can interact with ethinyl estradiol and etonogestrel. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using.

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