Olipudase alfa

Generic name: Olipudase Alfa
Brand names: Xenpozyme
Dosage form: intravenous powder for injection (rpcp 20 mg)
Drug class: Lysosomal enzymes

Usage of Olipudase alfa

Olipudase alfa is used to treat people with a genetic disorder called acid sphingomyelinase deficiency (ASMD).

Olipudase alfa may also be used for purposes not listed in this medication guide.

Olipudase alfa side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Olipudase alfa may cause serious side effects. Call your doctor at once if you have:

liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of olipudase alfa may include:

joint pain;

hives, rash, itching;

stuffy nose;

headache;

cough;

sore throat;

feeling like you might pass out;

eye redness;

fever, tiredness; or

diarrhea, stomach pain, vomiting, nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Olipudase alfa

Tell your doctor if you have ever had:

liver disease.

You may need to have a negative pregnancy test before starting this treatment.

May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using olipudase alfa and for at least 14 days after your last dose. Tell your doctor if you become pregnant.

Ask a doctor if it is safe to breastfeed while using olipudase alfa.

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How to use Olipudase alfa

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Olipudase alfa is injected into a vein.

Ask your doctor or pharmacist if you don't understand how to use an injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Doses are based on weight. Your dose may change if you gain or lose weight.

You will be watched for a short time to make sure you do not have an allergic reaction.

You will need frequent blood tests to check your liver function.

Follow all storage instructions provided with olipudase alfa. Your pharmacist can provide more information about how to store this medicine.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Olipudase alfa

Other drugs may affect olipudase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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