Olysio
Generic name: Simeprevir
Drug class:
Protease inhibitors
Usage of Olysio
Olysio is an antiviral medicine that prevents certain viruses from multiplying in your body. Simeprevir is used in combination with other medications to treat chronic hepatitis C in adults.
Olysio treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people.
Olysio must be given in combination with other antiviral medications and it should not be used alone.
Olysio is sometimes used in people who also have HIV. This medicine is not a treatment for HIV or AIDS.
Olysio side effects
Get emergency medical help if you have signs of an allergic reaction to Olysio: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Read all of your medication guides to learn about possible side effects of other medications you use in combination with simeprevir. Ask your doctor or pharmacist if you have any questions.
Call your doctor at once if you have:
If you take Olysio and you also take a heart rhythm medicine called amiodarone: This combination of medicines can cause dangerous side effects on your heart. Get medical help right away if you take these medicines and you have:
Common Olysio side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Olysio
You should not use Olysio if you are allergic to simeprevir. If you take Olysio with other antiviral medicines: There may be other reasons you should not take this combination treatment. Tell your doctor about all your medical conditions.
Your doctor will perform blood tests to make sure Olysio is the right treatment for your condition.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
Olysio is sometimes used in combination with ribavirin. Ribavirin can cause birth defects or death in an unborn baby.
While taking simeprevir with ribavirin, use at least 2 effective forms of birth control to prevent pregnancy, whether you are a man or a woman. Ribavirin use by either parent may cause birth defects.
Keep using 2 forms of birth control for at least 6 months after your last dose of ribavirin. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ribavirin.
It is not known whether simeprevir passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Olysio is not approved for use by anyone younger than 18 years old.
Relate drugs
- Aptivus
- Atazanavir
- Crixivan
- Boceprevir
- Darunavir
- Fosamprenavir
- Incivek
- Indinavir
- Invirase
- Kaletra
- Lexiva
- Lopinavir and ritonavir
- Nelfinavir
- Olysio
- Prezista
- Reyataz
- Saquinavir
- Simeprevir
- Telaprevir
- Tipranavir
- Victrelis
- Viracept
How to use Olysio
Take Olysio exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take with food.
Do not crush, chew, break, or open a Olysio capsule. Swallow the capsule whole.
You will need frequent blood tests to check your liver function.
If you have ever had hepatitis B, simeprevir can cause this condition to come back or get worse. You will need liver function tests during treatment and for several months after you stop using this medicine.
Read the medication guide or patient instructions provided with each medication in your combination therapy. Do not change your doses or medication schedule without your doctor's advice. Every person with chronic hepatitis C should remain under the care of a doctor.
You should not stop using Olysio suddenly. Stopping suddenly could make your condition harder to treat with hepatitis C antiviral medicine.
Store at room temperature away from moisture, heat, and light.
Warnings
If you have ever had hepatitis B, Olysio can cause this condition to come back or get worse. You will need frequent blood tests to check your liver function.
Olysio is used in combination with other medications. Read the medication guide or patient instructions provided with each medication in your combination therapy. Do not change your doses or medication schedule without your doctor's advice.
Call your doctor right away if you have symptoms of liver problems: vomiting, loss of appetite, feeling weak or tired, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Avoid exposure to sunlight or tanning beds. Sunlight can cause a severe rash or skin reaction while you are using simeprevir combination treatment. Use sunscreen and wear a hat, sunglasses, and protective clothing when you are outdoors.
What other drugs will affect Olysio
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may interact with simeprevir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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