Omeprazole and sodium bicarbonate

Generic name: Omeprazole And Sodium Bicarbonate
Drug class: Proton pump inhibitors

Usage of Omeprazole and sodium bicarbonate

Omeprazole and sodium bicarbonate is a combination medicine used to treat heartburn and other symptoms of gastroesophageal reflux disease (GERD).

omeprazole and sodium bicarbonate is also used to treat certain type of ulcers, or to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Omeprazole and sodium bicarbonate may also be used for purposes not listed in this medication guide.

Omeprazole and sodium bicarbonate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Omeprazole and sodium bicarbonate may cause serious side effects. Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody;

new or unusual pain in your wrist, back, hip, or thigh;

muscle twitching or tremor;

numbness or tingling in your face, arms, or legs;

confusion, dizziness;

a seizure;

low magnesium--dizziness, irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, cough or choking feeling;

kidney problems--fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;

new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight; or

vitamin B12 deficiency--shortness of breath, feeling lightheaded, irregular heartbeats, muscle weakness, pale skin, tiredness, mood changes.

Taking this medicine long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.

If you use omeprazole and sodium bicarbonate for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.

Common side effects of omeprazole and sodium bicarbonate may include:

headache;

nausea, vomiting, stomach pain, gas; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Omeprazole and sodium bicarbonate

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not take this medicine if you are allergic to omeprazole or sodium bicarbonate, or if:

you had breathing problems, kidney problems, or a severe allergic reaction after taking this medicine in the past; or

you are also taking any medication that contains rilpivirine (Edurant, Juluca, Complera, Odefsey).

This medicine contains sodium bicarbonate, a form of salt. Each capsule contains the equivalent of 300 mg of sodium. Each packet of powder contains the equivalent of 460 mg of sodium. If you are on a low-salt diet, you may not be able to use omeprazole and sodium bicarbonate. Talk with your doctor.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

a rare kidney disorder called Bartter's syndrome;

liver disease;

any allergies;

heart failure;

problems with acid-base (pH) balance in your body;

low levels of calcium, magnesium, or potassium levels in your blood;

if you are on a low-sodium diet; or

if you are of Asian descent.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Omeprazole and sodium bicarbonate is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Omeprazole and sodium bicarbonate

Usual Adult Dose for Duodenal Ulcer:

Omeprazole 20 mg orally once a day-Duration of therapy: 4 weeksComment: If patients are not healed after 4 weeks, treatment for another 4 weeks may be considered.Use: Short-term treatment of active duodenal ulcer

Usual Adult Dose for Gastric Ulcer:

Omeprazole 40 mg orally once a day-Duration of therapy: 4 to 8 weeksUse: Short-term treatment of active benign gastric ulcer

Usual Adult Dose for Gastroesophageal Reflux Disease:

Omeprazole 20 mg orally once a day-Duration of therapy: Up to 14 days (Over-the-Counter [OTC] formulations); Up to 4 weeks (prescription formulations)Comments:-The OTC formulation course of treatment may be repeated every 4 months as necessary.-The full effect of treatment may not be reached for up to 4 days.Uses:-Treatment of symptomatic gastroesophageal reflux disease (GERD) without esophageal erosions (prescription formulations)-Treatment of frequent heartburn occurring at least 2 days a week (OTC formulations)

Usual Adult Dose for Erosive Esophagitis:

Treatment: Omeprazole 20 mg orally once a day-Duration of therapy: 4 to 8 weeksMaintenance: Omeprazole 20 mg orally once a dayComments:Controlled studies for the efficacy in treatment of erosive esophagitis did not extend beyond 8 weeks.-An additional 4 to 8-week course of therapy may be considered in patients with a recurrence of erosive esophagitis or GERD symptoms after initial treatment.-Controlled studies for maintenance therapy did not extend beyond 12 months.Uses:-Short-term treatment of erosive esophagitis diagnosed by endoscopy-Maintenance of healing of erosive esophagitis

Usual Adult Dose for Gastrointestinal Hemorrhage:

Oral suspension: Omeprazole 40 mg orally, followed by 40 mg 6 to 8 hours later, and 40 mg orally once a day thereafter-Duration of therapy: 14 daysComment: Controlled studies did not extend past 12 months.Use: Reduction of risk of upper gastrointestinal bleeding in critically ill patients

Warnings

Omeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.

You may be more likely to have a broken bone while taking omeprazole and sodium bicarbonate long term or more than once per day.

This medicine contains sodium bicarbonate, a form of salt. Tell your doctor if you have Bartter's syndrome (a rare kidney disorder), or if you are on a low-salt diet.

What other drugs will affect Omeprazole and sodium bicarbonate

Tell your doctor about all your current medicines. Many drugs can affect omeprazole and sodium bicarbonate, especially:

clopidogrel;

cyclosporine;

digoxin;

methotrexate;

rifampin; or

St. John's wort.

This list is not complete and many other drugs may affect omeprazole and sodium bicarbonate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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