Orilissa
Generic name: Elagolix
Drug class:
Gonadotropin-releasing hormone antagonists
Usage of Orilissa
Orilissa binds to the same receptors in the body as a certain hormone that stimulates the production of sex hormones.
Orilissa works by lowering blood levels of estradiol and progesterone (female sex hormones).
Orilissa is used to treat moderate to severe pain caused by endometriosis.
Orilissa side effects
Get emergency medical help if you have signs of an allergic reaction to Orilissa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common Orilissa side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Orilissa
You should not use Orilissa if you are allergic to elagolix, or if:
You may need to have a negative pregnancy test before starting this treatment.
Do not use Orilissa if you are pregnant, and tell your doctor right away if you become pregnant. This medicine may cause miscarriage.
Orilissa may change your menstrual periods, making it harder for you to know if you are pregnant. Other signs of pregnancy could include breast tenderness, nausea, and weight gain.
Birth control pills can make elagolix less effective. Use a condom or diaphragm with spermicide to prevent pregnancy while using elagolix and for at least 1 week after your last dose.
To make sure Orilissa is safe for you, tell your doctor if you have:
Orilissa can lower your estrogen levels, which may cause bone loss (osteoporosis). Talk with your doctor about ways to keep your bones healthy during and after treatment with this medicine.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Relate drugs
- Antagon
- Cetrorelix
- Cetrorelix injectable
- Cetrotide
- Cetrotide injectable
- Elagolix
- Ganirelix
- Ganirelix Acetate
- Orgovyx
- Orilissa
- Relugolix
How to use Orilissa
Usual Adult Dose for Endometriosis:
150 mg orally once a day for 24 months For Women with Dyspareunia: -Consider 200 mg orally twice a day for 6 months Comments: -Use lowest effective dose, considering the severity of symptoms and treatment objectives. -The duration of treatment is limited because of bone loss. Use: For the management of moderate to severe pain associated with endometriosis.
Warnings
Do not use Orilissa if you are pregnant. Elagolix may cause miscarriage.
Hormonal birth control methods (birth control pills, injections, implants) could make Orilissa less effective. Use a condom or diaphragm with spermicide while you are taking elagolix and for at least 1 week after your last dose.
Elagolix can lower your estrogen levels, which may cause bone loss (osteoporosis). Talk with your doctor about ways to keep your bones healthy during and after treatment with this medicine.
What other drugs will affect Orilissa
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may interact with elagolix, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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