Oritavancin

Generic name: Oritavancin
Dosage form: intravenous powder for injection (1200 mg; 400 mg)
Drug class: Glycopeptide antibiotics

Usage of Oritavancin

Oritavancin is an antibiotic that is used to treat severe skin infections caused by bacteria.

Oritavancin may also be used for purposes not listed in this medication guide.

Oritavancin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel warm, itchy, dizzy, light-headed, sweaty, or have chills, tremors, chest pain, back pain, a rash, or redness in your face or upper body.

Oritavancin may cause serious side effects. Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after you receive oritavancin); or

pain, tenderness, redness, swelling, or warmth anywhere in your body.

Common side effects of oritavancin may include:

nausea, vomiting, diarrhea;

fever, chills;

itching;

headache; or

skin infections.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Oritavancin

You should not receive oritavancin if you are allergic to it, or if you will be using "unfractionated" heparin within 5 days after your receive oritavancin injection.

Tell your doctor if you have ever had:

an allergic reaction to medicines such as dalbavancin, telavancin, or vancomycin; or

if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

Tell your doctor if you are pregnant or breastfeeding.

Oritavancin is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Oritavancin

Usual Adult Dose for Skin and Structure Infection:

1200 mg via IV infusion (over 3 hours) onceComment: This drug should be given as a single dose.Use: For the treatment of acute bacterial skin and skin structure infections due to susceptible isolates of Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant isolates), Streptococcus pyogenes, S agalactiae, S dysgalactiae, S anginosus group (includes S anginosus, S intermedius, and S constellatus), and Enterococcus faecalis (vancomycin-susceptible isolates only)

Warnings

Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Oritavancin

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your other medicines, especially:

a blood thinner such as heparin or warfarin (Coumadin, Jantoven).

This list is not complete. Other drugs may affect oritavancin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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