Orphenadrine

Generic name: Orphenadrine
Dosage form: oral tablet, extended release (100 mg)
Drug class: Skeletal muscle relaxants

Usage of Orphenadrine

Orphenadrine is a muscle relaxer.

Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Orphenadrine may also be used for purposes not listed in this medication guide.

Orphenadrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Orphenadrine may cause serious side effects. Stop using orphenadrine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • painful or difficult urination;
  • little or no urination;
  • confusion, anxiety, agitation, tremors, hallucinations; or
  • pounding heartbeats or fluttering in your chest.
  • Common side effects of orphenadrine may include:

  • dizziness, drowsiness, weakness;
  • nausea, vomiting;
  • dry mouth; or
  • constipation.
  • This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Orphenadrine

    You should not use orphenadrine if you are allergic to it, or if you have:

  • urination problems;
  • an enlarged prostate;
  • glaucoma;
  • a stomach ulcer;
  • a blockage in your stomach or intestines;
  • trouble swallowing; or
  • myasthenia gravis.
  • To make sure orphenadrine is safe for you, tell your doctor if you have:

  • heart disease;
  • a heart rhythm disorder;
  • coronary artery disease; or
  • if you also use a narcotic (opioid) medication.
  • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It is not known whether orphenadrine passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

    Orphenadrine is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Orphenadrine

    Usual Adult Dose for Muscle Spasm:

    Extended-Release Tablets: 100 mg orally twice a day Parenteral Injection: 60 mg IV or IM every 12 hours as needed Use: As an adjunct to rest, physical therapy and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions.

    Warnings

    You should not take orphenadrine if you have urination problems, an enlarged prostate, glaucoma, a stomach ulcer or blockage in your digestive tract, trouble swallowing, or myasthenia gravis.

    What other drugs will affect Orphenadrine

    Taking orphenadrine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

    Other drugs may interact with orphenadrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

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