OsmoPrep

Generic name: Sodium Biphosphate And Sodium Phosphate (oral)
Drug class: Laxatives

Usage of OsmoPrep

OsmoPrep tablets contain a combination of sodium biphosphate and sodium phosphate, both are forms of phosphorus, which is a naturally occurring substance that is important in every cell in the body.

OsmoPrep is used in adults to treat constipation and to clean the bowel before a colonoscopy. OsmoPrep cleans your colon by causing you to have diarrhea.

Using OsmoPrep to clean your colon helps your doctor see the inside of your colon more clearly during the colonoscopy.

OsmoPrep side effects

Get emergency medical help if you have signs of an allergic reaction to OsmoPrep: hives; dizziness; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

no bowel movement after using this medicine;

severe stomach pain, rectal bleeding or bright red bowel movements;

fast, slow, or uneven heart rate;

little or no urination;

a seizure (black-out or convulsions); or

headache, dizziness, and vomiting.

Common OsmoPrep side effects may include:

bloating;

nausea, vomiting; or

stomach pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking OsmoPrep

You should not use OsmoPrep if you are allergic to sodium biphosphate and sodium phosphate, or if you have:

kidney disease (or if you have ever had a biopsy showing a kidney problem caused by too much phosphate);

a bowel obstruction;

a perforated bowel;

colitis or toxic megacolon; or

a history of gastric bypass surgery or stomach stapling.

In rare cases, OsmoPrep can cause kidney failure, especially if:

you have kidney disease;

you have congestive heart failure;

you have severe constipation or inflammatory bowel disease;

you take certain medicines to treat high blood pressure or heart disease;

you take an NSAID (nonsteroidal anti-inflammatory drug);

you are older than 55; or

you are dehydrated.

Do not use Osmoprep if you have already used it within the past 7 days.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;

heart disease;

dehydration or an electrolyte imbalance (such as high or low levels of calcium, potassium, sodium, phosphorous, or magnesium in your blood);

a seizure;

stomach surgery;

an intestinal disorder (such as ulcerative colitis or inflammatory bowel disease);

trouble swallowing, gastroesophageal reflux disease (GERD);

withdrawal from drug or alcohol addiction;

if you are on a low-salt diet; or

if you have already used a laxative for 7 days or longer.

Ask a doctor before using OsmoPrep if you are pregnant or breast-feeding.

Do not give this medicine to a child without medical advice.

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How to use OsmoPrep

Use OsmoPrep exactly as directed on the label, or as prescribed by your doctor.

Using too much OsmoPrep can cause rare but life-threatening side effects on your kidneys and heart.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

To keep from getting dehydrated, drink plenty of water or other clear liquid before, during, and after taking this medicine. Avoid milk, liquids that are colored red or purple, juice that contains pulp, or drinks that contain alcohol.

Carefully follow your doctor's dosing instructions about the timing of this medication and your procedure.

You may need to follow a special diet while treating constipation or preparing for your colonoscopy. Follow your doctor's instructions about any restrictions on food or beverages.

Store OsmoPrep at room temperature away from moisture and heat. Throw away any leftover medicine after your treatment ends.

Warnings

You should not use OsmoPrep if you have kidney disease, a bowel obstruction, a perforated bowel, colitis or toxic megacolon, or a history of gastric bypass surgery or stomach stapling.

In rare cases, this medicine can cause kidney failure, especially if you have: kidney disease, congestive heart failure, severe constipation, inflammatory bowel disease, if you are over 55, or if you are dehydrated. Using certain other medicines can also increase your risk of kidney problems.

Do not use more than 1 dose in any 24-hour period. If you do not get any results within 30 minutes after using OsmoPrep, call your doctor before using another dose.

Using too much OsmoPrep can cause rare but life-threatening side effects on your kidneys and heart.

What other drugs will affect OsmoPrep

Ask a doctor or pharmacist before using OsmoPrep with any other medications, especially:

a diuretic or "water pill";

blood pressure medication;

medicine to treat a kidney problem;

seizure medication;

a sedative - alprazolam, Diazepam, triazolam, Valium, Xanax, and others; or

NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may interact with sodium biphosphate and sodium phosphate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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