Oxcarbazepine

Generic name: Oxcarbazepine
Drug class: Dibenzazepine anticonvulsants

Usage of Oxcarbazepine

Oxcarbazepine is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain.

Oxcarbazepine is used either alone or with other medicines to treat partial seizures.

The Trileptal brand of oxcarbazepine is used as a single medicine in adults and children who are at least 4 years old. Trileptal is used with other medicines in adults and children who are at least 2 years old.

The Oxtellar XR brand of oxcarbazepine is used with other medicines in adults and children who are at least 6 years old.

Oxcarbazepine may also be used for purposes not listed in this medication guide.

Oxcarbazepine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Oxcarbazepine can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Call your doctor right away if you have nausea, lack of energy, confusion, feeling tired or irritable, severe weakness, muscle pain, or increased seizures.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Common side effects of oxcarbazepine may include:

  • dizziness, drowsiness, tiredness;
  • balance or coordination problems;
  • nausea, vomiting;
  • tremors or shaking;
  • double vision; or
  • rash.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Oxcarbazepine

    You should not take oxcarbazepine if you are allergic to oxcarbazepine or eslicarbazepine.

    Tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • mood problems or suicidal thoughts; or
  • an allergy to Carbamazepine (Carbatrol, Tegretol).
  • Some people have thoughts about suicide while taking oxcarbazepine. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

    Do not start or stop taking oxcarbazepine during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking oxcarbazepine for seizures.

    If you are pregnant, your name may be listed on a pregnancy registry to track the effects of oxcarbazepine on the baby.

    Oxcarbazepine can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

    You should not breast-feed while you are taking oxcarbazepine.

    Do not give this medicine to a child without medical advice. There are specific age restrictions for the use of oxcarbazepine in children, depending on the dose form and whether it is used alone or with other medicines.

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    How to use Oxcarbazepine

    Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

    Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

    Give the liquid directly from the oral syringe, or mix the medicine with a small glass of water. After using the syringe, rinse it with water and allow it to air dry.

    Take the oxcarbazepine extended-release tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.

    You may take the oxcarbazepine oral liquid or regular tablet with or without food.

    Swallow the extended-release tablet whole and do not crush, chew, or break it.

    You may need frequent blood tests.

    Do not stop using oxcarbazepine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

    In case of emergency, wear or carry medical identification to let others know you use oxcarbazepine.

    Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

    Store at room temperature away from moisture and heat. Throw away any unused liquid 7 weeks after opening the bottle.

    Warnings

    Seek medical treatment if you have symptoms of a serious drug reaction: skin rash, fever, swollen glands, flu-like symptoms, unusual bruising or bleeding, or yellowing of your skin or eyes.

    Call your doctor right away if you have symptoms of low sodium levels in your body, such as nausea, confusion, severe weakness, muscle pain, or increased seizures.

    Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

    Do not stop using oxcarbazepine suddenly.

    What other drugs will affect Oxcarbazepine

    Using oxcarbazepine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

    Many drugs can affect oxcarbazepine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

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