Palifermin

Generic name: Palifermin
Brand names: Kepivance
Dosage form: intravenous powder for injection (5.16 mg)
Drug class: Miscellaneous uncategorized agents

Usage of Palifermin

Palifermin is used to help prevent or heal mouth sores in people treated with chemotherapy and stem cell treatment.

Palifermin may also be used for purposes not listed in this medication guide.

Palifermin side effects

Get emergency medical help if you have signs of an allergic Reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Palifermin may cause serious side effects. Call your doctor at once if you have:

  • itching, rash, redness of skin; or
  • changes in mouth and tongue sensation, altered sense of taste.

    • Common side effects of palifermin may include:

  • fever;
  • swelling in your tongue;
  • itching or rash;
  • swelling or redness of skin; or
  • abnormal lab results.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Palifermin

    Using palifermin may increase the risk of some tumors to grow faster. Ask your doctor about your individual risk.

    May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using palifermin. Tell your doctor if you become pregnant.

    Palifermin may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using palifermin.

    Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.

    Relate drugs

    How to use Palifermin

    Usual Adult Dose for Mucositis:

    60 mcg/kg IV (as a bolus) once a day, administered for 3 consecutive days before and 3 consecutive days after myelotoxic therapyComments:-Prior to myelotoxic therapy: The third dose should be administered 24 to 48 hours prior to beginning the myelotoxic agent.-Following myelotoxic therapy: The first dose should be administered on the day of hematopoietic stem cell infusion after the infusion is complete, AND at least 7 days after the most recent dose of this drug.Uses:-Decrease the incidence and duration of severe oral mucositis in patients with hematologic malignancies receiving myelotoxic therapy in the setting of autologous hematopoietic stem cell support-Supportive care for preparative regiments predicted to result in greater than or equal to WHO Grade 3 mucositis in the majority of patients

    Warnings

    Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

    What other drugs will affect Palifermin

    Other drugs may affect palifermin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords