Pentosan polysulfate sodium

Generic name: Pentosan Polysulfate Sodium
Brand names: Elmiron
Drug class: Miscellaneous genitourinary tract agents

Usage of Pentosan polysulfate sodium

Pentosan polysulfate sodium is used to treat bladder pain and discomfort caused by cystitis (bladder inflammation or irritation).

Pentosan polysulfate sodium is for use in adults and children at least 16 years old.

Pentosan polysulfate sodium may also be used for purposes not listed in this medication guide.

Pentosan polysulfate sodium side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Pentosan polysulfate sodium may cause serious side effects. Call your doctor at once if you have:

  • nosebleeds, bleeding gums;
  • blood in your urine or stools;
  • rectal bleeding;
  • coughing up blood;
  • a light-headed feeling, like you might pass out; or
  • vision problems (blurred vision, trouble reading, trouble seeing in low light).

    • Common side effects of pentosan polysulfate sodium may include:

  • bruising, blood in your stools;
  • hair loss;
  • nausea, diarrhea, upset stomach;
  • headache;
  • swelling, weight gain;
  • dizziness;
  • rash; or
  • abnormal liver function tests.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Pentosan polysulfate sodium

    You should not use pentosan polysulfate sodium if you are allergic to it.

    Tell your doctor if you have ever had:

  • a bleeding or blood clotting disorder;
  • eye problems (especially a problem with your retina) in you or a family member;
  • an aneurysm or stroke;
  • a stomach ulcer, intestinal polyps or diverticulitis; or
  • liver disease.

    • Tell your doctor if you are pregnant or breastfeeding.

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    How to use Pentosan polysulfate sodium

    Usual Adult Dose for Cystitis:

    100 mg orally 3 times a dayUse: For the relief of bladder pain or discomfort associated with interstitial cystitis

    Usual Pediatric Dose for Cystitis:

    16 years or older: 100 mg orally 3 times a dayUse: For the relief of bladder pain or discomfort associated with interstitial cystitis

    Warnings

    Taking pentosan polysulfate sodium can make it easier for you to bleed. Call your doctor at once if you have any unusual bleeding (nosebleed, blood in your urine or stools, rectal bleeding, coughing up blood, bleeding gums).

    What other drugs will affect Pentosan polysulfate sodium

    Tell your doctor about all your other medicines, especially:

  • a blood thinner--warfarin, Coumadin, Jantoven;
  • medication used to prevent blood clots--apixaban, heparin, rivaroxaban, Eliquis, Xarelto, and others; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac, indomethacin, meloxicam, and others.

    • This list is not complete. Other drugs may affect pentosan polysulfate sodium, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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