Pine Needle Oil

Generic name: Cedrus Deodara (Roxb. Ex D. Don) G. Don, Pinus Densiflora Sieb. Et Zucc., Pinus Sylvestris L.
Brand names: Pine Needle Oil

Usage of Pine Needle Oil

Research reveals no clinical data for the use of pine needle oil.

Antibacterial/Antifungal activity

In vitro data

In a study evaluating the chemical composition and antioxidant and antimicrobial activities of essential oil from pine needles, pine needle oil showed inhibitory activity against the bacteria EscheriChia coli, Staphylococcus aureus, Bacillus subtilis, and Bacillus cereus, as well as the fungi Aspergillus niger, Penicillium citrinum, Rhizopus oryzae, and Aspergillus flavus; however, gentamicin was more effective.Zeng 2012 Another study of an aqueous extract from pine needles documented similar antibacterial activity against food spoilage and pathogenic bacteria, including Micrococcus luteus and Proteus vulgaris.Feng 2010 Antifungal activity was also documented against Fusarium culmorum, Fursarium solani, and Fusarium poae.Krauze-Baranowska 2002 Pine needle oil in combination with ascorbic acid inhibited tissue browning and reduced microbial growth on fresh-cut apple slices.Zeng 2011

Antioxidant activity

In vitro data

Pine needle oil demonstrated antioxidant activity against hydrogen peroxide–treated brain neuroblastoma cells in one studyKa 2005 and 1,1-dihenyl-1-picryhydrazl radical scavenging activity in another study.Park 2011

Cancer

In vitro data

Studies have demonstrated inhibitory activity of alpha-pinene from pine needle oil on tumor growth by blocking cell growth in the G2/M phase of the cell cycle, down-regulating Cdc25C mRNA and protein expression, and reducing cycle dependence on kinase 1 (cyclin-dependent protein kinase 1) activity. Activity has been demonstrated in human cancer cell lines, including liver and breast cancers.Chen 2014, Chen 2015, Kang 2016, Qiu 2018

Obesity

Animal data

Pine needle oil supplementation reduced body weight gain and visceral fat mass in rats treated with a high-fat diet. Total cholesterol, triglycerides, and leptin levels in plasma were also reduced. Histological findings also documented reduced fatty liver tissue or steatosis.Jeon 2013, Jeon 2006

Wound healing

Animal data

Pine needle oil counteracted dermal ear inflammation and second-degree scald paw burns in mice. The oil counteracted the tactile pain (by blocking pain transmission or activation of calcium channels by adenosine triphosphate) and soft tissue injury caused by the burn.Clark 2014

Pine Needle Oil side effects

Limited clinical data are available. Topical preparations containing pine needle oil are generally well tolerated. Allergic contact dermatitis from various pine needle oil fragrance components has been documented.Nardelli 2009

Before taking Pine Needle Oil

Avoid use due to documented adverse effects.

How to use Pine Needle Oil

No clinical data are available to provide dosing recommendations. Pine needle oil is available commercially in many products and marketed for numerous health conditions and for aromatherapy use. Pine needle tea is also marketed as an overall panacea.

Warnings

Avoid use in cases of hypersensitivity to any components of pine needle oil.

Teratogenic activity of alkaloids from pine and spruce needles was confirmed in pregnant range cows.Tawara 1993, Virjamo 2014

What other drugs will affect Pine Needle Oil

Data are lacking concerning specific drug interactions.

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