Pirtobrutinib

Generic name: Pirtobrutinib
Brand names: Jaypirca
Dosage form: oral tablet (100 mg; 50 mg)
Drug class: BTK inhibitors

Usage of Pirtobrutinib

Pirtobrutinib is used in adults to treat mantle cell lymphoma.

Pirtobrutinib may also be used for purposes not listed in this medication guide.

Pirtobrutinib side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Pirtobrutinib may cause serious side effects. Call your doctor at once if you have:

chest pressure, racing or pounding heartbeats, fluttering in your chest, feeling short of breath;

signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding;

bleeding inside your body--weakness, dizziness; pink or brown urine; abnormal vaginal bleeding; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or

low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects of pirtobrutinib may include:

bruising;

tiredness;

diarrhea;

swelling;

muscle, joint, or bone pain; or

fever, chills, cough with mucus, chest pain, feeling short of breath.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Pirtobrutinib

Tell your doctor if you have or have ever had:

an infection or have been told you are at an increased risk of infection;

recent surgery, or plan to have surgery or a dental procedure;

bleeding problems or are taking a blood thinner medicine;

heart rhythm problems;

high blood pressure;

other types of cancer, including skin cancer; or

kidney disease.

You will need to take a pregnancy test before treatment with pirtobrutinib.

May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using pirtobrutinib and for at least 1 week after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed while using pirtobrutinib, and for at least 1 week after your last dose.

Relate drugs

How to use Pirtobrutinib

Usual Adult Dose for Mantle Cell Lymphoma:

200 mg orally once dailyLength of Therapy: Until disease progression or unacceptable toxicity occurs.Comments:-Swallow tablets whole with water. Do not cut, crush, or chew tablets.-This indication is approved under accelerated approval based on response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.Use: For the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy, including a BTK inhibitor.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Pirtobrutinib

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Many drugs can affect pirtobrutinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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