Plecanatide

Generic name: Plecanatide
Brand names: Trulance
Dosage form: oral tablet (3 mg)
Drug class: Guanylate cyclase-C agonists

Usage of Plecanatide

Plecanatide is used to treat chronic idiopathic constipation, or irritable bowel syndrome with constipation.

Plecanatide may also be used for purposes not listed in this medication guide.

Plecanatide side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Diarrhea is a common side effect of plecanatide. Stop using plecanatide and call your doctor at once if your diarrhea is severe.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Plecanatide

You should not use plecanatide if you are allergic to it, or if you have:

a blockage in your intestines.

Do not give this medicine to a child younger than 6 years old.

Avoid using plecanatide in anyone younger than 18 years old. In animal studies, plecanatide caused severe dehydration leading to death.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Plecanatide

Usual Adult Dose for Chronic Idiopathic Constipation:

3 mg orally once a dayUse: Treatment of chronic idiopathic constipation (CIC)

Usual Pediatric Dose for Chronic Idiopathic Constipation:

-Under Age 6 Years: Contraindicated.-Age 6 to Under 18 Years: Not recommended.

Warnings

You should not use plecanatide if you have a blockage in your intestines.

Do not give plecanatide to a child younger than 6 years old. Plecanatide is not approved for use by anyone younger than 18 years old.

What other drugs will affect Plecanatide

Other drugs may affect plecanatide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.