Precedex

Generic name: Dexmedetomidine
Drug class: Miscellaneous anxiolytics , Antineoplastic Agents

Usage of Precedex

Dexmedetomidine injection is used to help you sleep (sedate) before or during surgery or other medical procedures. This medicine is also used to sedate intubated and mechanically ventilated patients during treatment in the intensive care unit (ICU).

This medicine is to be given only by or under the direct supervision of your doctor.

Precedex side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision

chest pain or discomfort

confusion

coughing

dizziness

dizziness, faintness, or lightheadedness when getting suddenly up from a lying or sitting position

headache

irregular, fast or slow, or shallow breathing

nervousness

pale or blue lips, fingernails, or skin

pounding in the ears

slow or fast heartbeat

sweating

trouble breathing

unusual tiredness or weakness

Less common

Bleeding gums

bloody urine

coughing that sometimes produces a pink frothy sputum

coughing up blood

drowsiness

dry mouth

extremely high fever or body temperature

fast, pounding, or irregular heartbeat or pulse

fever

flushed, dry skin

fruit-like breath odor

increased hunger

increased menstrual flow or vaginal bleeding

increased thirst

increased urination

loss of appetite

lower back or side pain

mood or mental changes

muscle cramps in the hands, arms, feet, legs, or face

muscle spasms or twitching seizures

nausea

nosebleeds

numbness and tingling around the mouth, fingertips, or feet

pale, clammy skin

paralysis

prolonged bleeding from cuts

red or black, tarry stools

red or dark brown urine

seizures

stomach cramps

swelling of face, fingers, legs, or ankles

tremor

unexplained weight gain or loss

vomiting

Incidence not known

Chest tightness

confusion as to time, place, or person

frequent urination

holding false beliefs that cannot be changed by fact

increased volume of pale, dilute urine

irritability

no blood pressure

pain or discomfort in the arms, jaw, back, or neck

restlessness

seeing, hearing, or feeling things that are not there

shakiness

sleepiness

slow to respond

slurred speech

stomach pain

stopping of the heart

unconsciousness

unusual excitement, nervousness, or restlessness

weakness or heaviness of the legs

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Anxiety

constipation

shaking

Incidence not known

Hives, itching, rash

redness of the skin

seeing flashes or sparks of light

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Precedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of dexmedetomidine injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dexmedetomidine injection in the elderly. However, elderly patients are more likely to have serious unwanted effects (eg, low blood pressure, slow heartbeat), which may require caution and an adjustment in the dose for patients receiving this medicine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Bepridil

Cisapride

Dronedarone

Mesoridazine

Pimozide

Piperaquine

Saquinavir

Sparfloxacin

Terfenadine

Thioridazine

Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acepromazine

Alfentanil

Alfuzosin

Alprazolam

Amiodarone

Amisulpride

Amitriptyline

Amobarbital

Anagrelide

Anileridine

Apomorphine

Aripiprazole

Aripiprazole Lauroxil

Arsenic Trioxide

Asenapine

Astemizole

Atazanavir

Azithromycin

Baclofen

Bedaquiline

Benperidol

Benzhydrocodone

Bromazepam

Bromopride

Buprenorphine

Buserelin

Buspirone

Butabarbital

Butorphanol

Calcium Oxybate

Cannabidiol

Cannabis

Carbinoxamine

Carisoprodol

Carphenazine

Ceritinib

Cetirizine

Chloral Hydrate

Chlordiazepoxide

Chloroquine

Chlorpromazine

Chlorzoxazone

Ciprofloxacin

Citalopram

Clarithromycin

Clobazam

Clofazimine

Clomipramine

Clonazepam

Clorazepate

Clothiapine

Clozapine

Codeine

Crizotinib

Cyclobenzaprine

Dabrafenib

Daridorexant

Dasatinib

Degarelix

Delamanid

Desipramine

Deslorelin

Deutetrabenazine

Diacetylmorphine

Diazepam

Dichloralphenazone

Difenoxin

Dihydrocodeine

Diphenhydramine

Diphenoxylate

Disopyramide

Dofetilide

Dolasetron

Domperidone

Donepezil

Doxepin

Doxylamine

Droperidol

Ebastine

Efavirenz

Encorafenib

Enflurane

Entrectinib

Eribulin

Erythromycin

Escitalopram

Esketamine

Estazolam

Eszopiclone

Ethchlorvynol

Ethopropazine

Ethylmorphine

Famotidine

Felbamate

Fentanyl

Fexinidazole

Fingolimod

Flecainide

Flibanserin

Fluconazole

Flunitrazepam

Fluoxetine

Fluphenazine

Flurazepam

Fluspirilene

Formoterol

Foscarnet

Fosphenytoin

Fospropofol

Gabapentin

Gabapentin Enacarbil

Galantamine

Gatifloxacin

Gemifloxacin

Glasdegib

Gonadorelin

Goserelin

Granisetron

Halazepam

Halofantrine

Haloperidol

Halothane

Hexobarbital

Histrelin

Hydrocodone

Hydromorphone

Hydroquinidine

Hydroxychloroquine

Hydroxyzine

Ibutilide

Iloperidone

Imipramine

Inotuzumab Ozogamicin

Iobenguane I 131

Isoflurane

Itraconazole

Ivabradine

Ivosidenib

Ketamine

Ketazolam

Ketobemidone

Ketoconazole

Lacosamide

Lapatinib

Lefamulin

Lemborexant

Lenvatinib

Leuprolide

Levocetirizine

Levofloxacin

Levorphanol

Lofexidine

Lorazepam

Loxapine

Lumefantrine

Macimorelin

Magnesium Oxybate

Meclizine

Mefloquine

Melperone

Meperidine

Mephobarbital

Meprobamate

Meptazinol

Metaxalone

Methadone

Methdilazine

Methocarbamol

Methohexital

Methotrimeprazine

Methylene Blue

Metoclopramide

Metronidazole

Midazolam

Mifepristone

Mizolastine

Mobocertinib

Molindone

Moricizine

Morphine

Morphine Sulfate Liposome

Moxifloxacin

Nafarelin

Nalbuphine

Nelfinavir

Nicomorphine

Nilotinib

Nitrazepam

Nitrous Oxide

Norfloxacin

Octreotide

Ofloxacin

Olanzapine

Ondansetron

Opium

Opium Alkaloids

Orphenadrine

Osilodrostat

Osimertinib

Oxaliplatin

Oxazepam

Oxycodone

Oxymorphone

Paliperidone

Panobinostat

Papaveretum

Papaverine

Paregoric

Paroxetine

Pasireotide

Pazopanib

Pentamidine

Pentazocine

Pentobarbital

Perampanel

Perazine

Periciazine

Perphenazine

Phenobarbital

Pimavanserin

Pipamperone

Piperacetazine

Pipotiazine

Piritramide

Pitolisant

Ponesimod

Posaconazole

Potassium Oxybate

Prazepam

Pregabalin

Primidone

Probucol

Procainamide

Prochlorperazine

Promazine

Promethazine

Propafenone

Propofol

Protriptyline

Quazepam

Quetiapine

Quinidine

Quinine

Ramelteon

Ranolazine

Remifentanil

Remimazolam

Remoxipride

Ribociclib

Risperidone

Ritonavir

Ropeginterferon Alfa-2b-njft

Scopolamine

Secobarbital

Selpercatinib

Sertindole

Sertraline

Sevoflurane

Siponimod

Sodium Oxybate

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Sufentanil

Sulpiride

Sultopride

Sunitinib

Suvorexant

Tacrolimus

Tamoxifen

Tapentadol

Telaprevir

Telavancin

Telithromycin

Temazepam

Tetrabenazine

Thiethylperazine

Thiopental

Thiopropazate

Tilidine

Tizanidine

Tolonium Chloride

Tolterodine

Topiramate

Toremifene

Tramadol

Trazodone

Triazolam

Triclabendazole

Trifluoperazine

Trifluperidol

Triflupromazine

Trimeprazine

Trimipramine

Triptorelin

Vandetanib

Vardenafil

Vemurafenib

Venlafaxine

Vilanterol

Vinflunine

Voclosporin

Voriconazole

Vorinostat

Zaleplon

Zolpidem

Zopiclone

Zotepine

Zuclopenthixol

Zuranolone

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Relate drugs

How to use Precedex

A nurse or other trained health professional will give you this medicine in a medical facility. This medicine is given through a needle placed in one of your veins.

Warnings

It is very important that your doctor check your progress closely while you are receiving this medicine to make sure this medicine is working properly and to check for unwanted effects.

This medicine may cause hypotension (low blood pressure). Check with your doctor right away if you have blurred vision, confusion, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, sweating, or unusual tiredness or weakness.

Check with your doctor right away if you have chest pain or discomfort, lightheadedness, dizziness, or fainting, slow or irregular heartbeat, trouble breathing, or unusual tiredness. These may be symptoms of bradycardia (slow heartbeat).

This medicine may cause hyperthermia (high body temperature). Check with your doctor right away if you have dizziness, fast, shallow breathing, fast, weak heartbeat, muscle cramps, pale, clammy skin, thirst, or extremely high fever or body temperature.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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