Prepopik

Generic name: Citric Acid, Magnesium Oxide, And Sodium Picosulfate
Drug class: Laxatives

Usage of Prepopik

Prepopik contains a combination of citric acid, magnesium oxide, and sodium picosulfate.

Prepopik causes diarrhea for the purpose of cleaning your colon before a colonoscopy. Cleaning the colon allows the inside of your colon to be seen more clearly on the colonoscopy.

Prepopik is for use in adults and children at least 9 years old.

Prepopik side effects

Get emergency medical help if you have signs of an allergic reaction to Prepopik: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have:

  • a light-headed feeling, like you might pass out;
  • confusion;
  • irregular heartbeats;
  • a seizure;
  • little or no urination;
  • severe nausea or vomiting;
  • painful bloating, severe stomach cramps;
  • rectal bleeding; or
  • trouble swallowing, trouble drinking liquids.
  • Common Prepopik side effects may include:

  • stomach pain;
  • nausea, vomiting; or
  • headache.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Prepopik

    You should not use Prepopik if you are allergic to citric acid, magnesium oxide, or sodium picosulfate, or if you have:

  • kidney disease;
  • a bowel obstruction, ileus, colitis or toxic megacolon;
  • a dilated intestine;
  • a perforation (a hole or tear) of your intestines; or
  • slow digestion.
  • To make sure Prepopik is safe for you, tell your doctor if you have ever had:

  • dehydration and an electrolyte imbalance (such as low levels of potassium, magnesium, or sodium in your blood);
  • a stomach or intestinal disorder, including ulcerative colitis;
  • gastroesophageal reflux disease (GERD);
  • kidney problems;
  • heart problems;
  • a seizure;
  • alcohol withdrawal; or
  • if you have recently used a sedative like Valium or Xanax (diazepam, alprazolam, lorazepam, and others).
  • Tell your doctor if you are pregnant or breastfeeding.

    Relate drugs

    How to use Prepopik

    Use Prepopik exactly as directed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

    Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

    It is especially important to follow all instructions about what to eat or drink in the days before your colon prep.

    You must dilute the Prepopik powder with 5 ounces of cold water before taking it.

    Do not eat solid food once you start taking this medicine. Stop drinking all fluids at least 2 hours before the colonoscopy.

    You will need to drink extra water once you start your colon prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.

    Prepopik can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats that can cause death.

    Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

    Store at room temperature, away from moisture and heat.

    Warnings

    Prepopik can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats that can cause death.

    The risk of dehydration is highest in people with heart problems or kidney disease, or if you take certain other medicines. Tell your doctor about all your current medicines and any you start or stop using.

    Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

    What other drugs will affect Prepopik

    Prepopik can make it harder for your body to absorb other medicines you take by mouth within 1 hour before your colon prep.

    If you take any of the following medicines, take them at least 2 hours before or not less than 6 hours after you take Prepopik:

  • chlorpromazine;
  • digoxin;
  • iron;
  • penicillamine; o
  • certain antibiotics, such as ciprofloxacin, doxycycline, levofloxacin, minocycline, moxifloxacin, norfloxacin, or tetracycline.
  • Tell your doctor about all your other medicines, especially:

  • a laxative;
  • a diuretic or "water pill";
  • heart or blood pressure medication;
  • medicine to treat a kidney problem;
  • medicine to treat depression or mental illness;
  • seizure medication; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
  • This list is not complete. Other drugs may interact with citric acid, magnesium oxide, and sodium picosulfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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