Prohance

Generic name: Gadoteridol
Drug class: Magnetic resonance imaging contrast media

Usage of Prohance

Prohance is a contrast agent that has magnetic properties. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

Prohance is used to help diagnose certain disorders of the head and neck, or brain and spine (central nervous system).

Prohance may also be used for purposes not listed in this medication guide.

Prohance side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects of gadoteridol may occur up to several days after injection.

Prohance can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

burning, itching, swelling, scaling, and tightening or hardening of your skin;

muscle weakness;

joint stiffness in your arms, hands, legs, or feet;

deep bone pain in your ribs or your hips;

trouble moving; or

skin redness or discoloration.

Also call your doctor at once if you have:

kidney problems--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;

a seizure (convulsions); or

a light-headed feeling, like you might pass out.

Common side effects of Prohance may include:

nausea; or

unusual or unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Prohance

Prohance can cause a life-threatening condition in people with advanced kidney disease. You should not receive this medication if you have kidney disease or if you are on dialysis.

Prohance can stay in your body for months or years after you receive this medicine. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent, and provide the date of your last scan.

You should not receive Prohance if you are allergic to it.

Tell your doctor if you have ever had:

kidney problems;

any type of reaction to a contrast agent;

diabetes;

high blood pressure;

liver disease;

anemia or other red blood cell disorder;

a seizure;

asthma, hay fever, food or drug allergies;

an injury, surgery, or severe infection; or

if you are over 60 years old.

Tell your doctor if you are pregnant or breastfeeding.

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How to use Prohance

Prohance is given as an infusion into a vein. A healthcare provider will give you this injection.

Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.

Warnings

Prohance can cause a life-threatening condition in people with advanced kidney disease. Before receiving Prohance, tell your doctor if you have kidney disease or if you are on dialysis. You may not be able to receive this medicine. Also tell your doctor if you have recently received any contrast agents similar to this medicine.

What other drugs will affect Prohance

Other drugs may affect Prohance, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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