Protopam Chloride

Generic name: Pralidoxime
Drug class: Antidotes

Usage of Protopam Chloride

Protopam Chloride is used as an antidote to treat poisoning caused by chemicals, pesticides (insect sprays), or drugs used to treat a muscle disorder.

This medication is not effective as an antidote for all types of pesticide poisonings.

Protopam Chloride may also be used for purposes not listed in this medication guide.

Protopam Chloride side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some of the side effects of pralidoxime may be similar to the symptoms of poisoning. Your caregivers will watch you closely to determine whether your body is responding well to the medication, or if you are having any serious side effects.

Tell your caregivers right away if you have:

  • fast or pounding heartbeats;
  • chest tightness, shortness of breath;
  • anxiety, dizziness, or nervousness;
  • numbness or tingling;
  • painful or difficult urination;
  • little or no urination;
  • vision problems; or
  • muscular weakness.

    • Side effects may be more likely in older adults.

    Common side effects of Protopam Chloride may include:

  • pain for up to an hour after injection into a muscle;
  • trouble breathing;
  • vision changes;
  • nausea;
  • fast heartbeats, increased blood pressure;
  • headache, dizziness, drowsiness; or
  • muscle weakness.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Protopam Chloride

    If possible during an emergency, tell your caregivers if you've ever had:

  • an allergy to any medication;
  • liver or kidney disease;
  • heart problems; or
  • high blood pressure.

    • If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

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    How to use Protopam Chloride

    Protopam Chloride is injected into a muscle, under the skin, or into a vein.

    Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.

    You may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison.

    Warnings

    If you receive Protopam Chloride during an emergency, make sure any follow-up doctor knows you received Protopam Chloride.

    What other drugs will affect Protopam Chloride

    Tell your doctor about all your other medicines, especially:

  • atropine;
  • morphine;
  • a barbiturate such as phenobarbital;
  • medicine to treat anxiety, mood disorders, or mental illness such as schizophrenia; or
  • a bronchodilator--aminophylline, theophylline.

    • This list is not complete. Other drugs may affect Protopam Chloride, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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