Prucalopride

Generic name: Prucalopride
Brand names: Motegrity
Dosage form: oral tablet (1 mg; 2 mg)
Drug class: Serotoninergic neuroenteric modulators

Usage of Prucalopride

Prucalopride is used to treat chronic idiopathic constipation (constipation without a known cause).

Prucalopride may also be used for purposes not listed in this medication guide.

Prucalopride side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Prucalopride may cause serious side effects. Stop using prucalopride and call your doctor at once if you have:

unusual changes in mood or behavior;

ongoing or worsening depression;

thoughts about suicide or hurting yourself; or

if you feel sad or hopeless.

Common side effects of prucalopride may include:

nausea, vomiting, diarrhea;

stomach pain, bloating, gas;

headache;

dizziness; or

feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Prucalopride

You should not use prucalopride if you are allergic to it, or if you have:

a blockage in your intestines;

severe constipation;

inflammatory bowel disease (Crohn's disease, ulcerative colitis);

toxic megacolon; or

perforation (a hole or tear) of your intestines.

Tell your doctor if you have ever had:

kidney disease;

depression;

a mood disorder; or

suicidal thoughts.

Tell your doctor if you are pregnant or breast-feeding.

Prucalopride is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Prucalopride

Usual Adult Dose for Chronic Idiopathic Constipation:

2 mg orally once a dayUse: Treatment of chronic idiopathic constipation (CIC)

Warnings

You should not use prucalopride if you have a blockage in your intestines, Crohn's disease, ulcerative colitis, or intestinal perforation.

What other drugs will affect Prucalopride

Other drugs may affect prucalopride, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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