Pseudoephedrine

Generic name: Pseudoephedrine
Drug class: Decongestants

Usage of Pseudoephedrine

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes.

Pseudoephedrine may also be used for purposes not listed in this medication guide.

Pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction to pseudoephedrine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using pseudoephedrine and call your doctor at once if you have a serious side effect such as:

fast, pounding, or uneven heartbeat;

severe dizziness or anxiety;

easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

dangerously high blood pressure (severe headache, blurred vision, ringing in your ears, anxiety, confusion, chest pain, trouble breathing, uneven heart rate, seizure).

Less serious pseudoephedrine side effects may include:

loss of appetite;

warmth, tingling, or redness under your skin;

feeling restless or excited (especially in children);

sleep problems (insomnia); or

skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Pseudoephedrine

Do not use pseudoephedrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Do not use this medication if you are allergic to pseudoephedrine or to other decongestants, diet pills, stimulants, or ADHD medications.

Ask a doctor or pharmacist if it is safe for you to take pseudoephedrine if you have:

heart disease or high blood pressure;

diabetes; or

a thyroid disorder.

FDA pregnancy category C. It is not known whether pseudoephedrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use pseudoephedrine without telling your doctor if you are breast-feeding a baby.

Artificially sweetened liquid cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

Relate drugs

How to use Pseudoephedrine

Usual Adult Dose of Pseudoephedrine for Nasal Congestion:

Immediate release: 30 to 60 mg orally every 4 to 6 hours as needed. Sustained release: 120 mg orally every 12 hours as needed. Sustained release suspension: 45 to 100 mg orally every 12 hours as needed. Maximum daily dose is 240 mg/day.

Usual Pediatric Dose of Pseudoephedrine for Nasal Congestion:

2 years to 5 years: Immediate release: 15 mg every 6 hours. Sustained release suspension: 12.5 to 25 mg orally every 12 hours as needed. Maximum daily dose is 60 mg/day. Alternative dosing: 1 mg/kg/dose every 6 hours; maximum dose: 15 mg. 6 years to 12 years: Immediate release: 30 mg every 6 hours. Sustained release suspension: 25 to 50 mg orally every 12 hours as needed. Maximum daily dose is 120 mg/day. over 12 years: Immediate release: 30 to 60 mg orally every 4 to 6 hours as needed. Sustained release: 120 mg orally every 12 hours as needed. Sustained release suspension: 50 to 100 mg orally every 12 hours as needed. Maximum daily dose is 240 mg/day.

Warnings

Do not give pseudoephedrine to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Ask a doctor or pharmacist before using any other cough or cold medicine. Pseudoephedrine or other decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains pseudoephedrine or a decongestant. Do not use pseudoephedrine if you have used a MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

What other drugs will affect Pseudoephedrine

Tell your doctor about all other medicines you use, especially:

blood pressure medications;

a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or

an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan), nortriptyline (Pamelor), and others.

This list is not complete and other drugs may interact with pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Disclaimer

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