Pyridoxine

Generic name: Pyridoxine (vitamin B6)
Drug class: Vitamins

Usage of Pyridoxine

Pyridoxine is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body.

Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine may also be used for purposes not listed in this medication guide.

Pyridoxine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Pyridoxine may cause serious side effects. Call your doctor at once if you have:

  • decreased sensation to touch, temperature, and vibration;
  • loss of balance or coordination;
  • numbness in your feet or around your mouth;
  • clumsiness in your hands; or
  • feeling tired.
  • Common side effects of pyridoxine may include:

  • nausea;
  • headache;
  • drowsiness; or
  • mild numbness or tingling.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Pyridoxine

    You should not use pyridoxine if you have ever had an allergic reaction to it.

    Ask a doctor or pharmacist if it is safe for you to use this medicine if:

  • you have any other medical conditions;
  • you take other medications or herbal products; or
  • you are allergic to any drugs or foods.
  • To make sure you can safely receive injectable pyridoxine, tell your doctor if you have heart disease or kidney disease.

    Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different. High doses of pyridoxine can harm a nursing baby.

    Do not give this medicine to a child without medical advice.

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    How to use Pyridoxine

    Usual Adult Dose for Drug Induced Vitamin/Mineral Deficiency:

    Isoniazid induced deficiencies: 100 mg intramuscularly or intravenously once a day followed by a 30 mg maintenance dose dailyPoisoning caused by ingestion of over 10 grams of isoniazid: Give an equal amount of pyridoxine, starting with 4 grams intravenously followed by 1 gram intramuscularly every 30 minutes

    Usual Adult Dose for Dietary Supplement:

    Injectable: Dietary deficiency: 10 to 20 mg intramuscularly or intravenously once a day for 3 weeks-Follow up with an oral multivitamin containing 2 to 5 mg pyridoxine daily for several weeks.-Correct poor dietary habits; prescribe a well balanced diet.Recommended dietary allowance of vitamin B6:18 years, male: 1.3 mg/day18 years, female: 1.2 mg/day19 to 50 years (both genders): 1.3 mg/day51 to 70 years, male: 1.7 mg/day51 to 70 years, female: 1.5 mg/dayPregnancy: 1.9 mg/dayLactation: 2 mg/day

    Usual Adult Dose for Seizures:

    Injectable: Vitamin B6 dependency syndrome: Up to 600 mg intramuscularly or intravenously daily, with a daily intake of 30 mg for life

    Usual Pediatric Dose for Dietary Supplement:

    Adequate intake of vitamin B6:0 to 6 months: 0.1 mg/day7 to 12 months: 0.3 mg/dayEstimated adequate intake of vitamin B6:1 to 3 years: 0.4 mg/day4 to 8 years: 0.5 mg/day9 to 13 years: 0.8 mg/day14 to 18 years, male: 1.1 mg/day14 to 18 years, female: 1 mg/dayRecommended dietary allowance of vitamin B6:1 to 3 years: 0.5 mg/day4 to 8 years: 0.6 mg/day9 to 13 years: 1 mg/day14 to 18 years, male: 1.3 mg/day14 to 18 years, female: 1.2 mg/day

    Warnings

    Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

    What other drugs will affect Pyridoxine

    Other drugs may interact with pyridoxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

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