Qtern

Generic name: Dapagliflozin And Saxagliptin
Drug class: Antidiabetic combinations

Usage of Qtern

Qtern contains a combination of Dapagliflozin and Saxagliptin. Dapagliflozin and saxagliptin are oral diabetes medicines that help control blood sugar levels. Dapagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Saxagliptin works by regulating the levels of insulin your body produces after eating.

Qtern is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Qtern is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.

Qtern is not for treating type 1 diabetes or diabetic ketoacidosis.

Qtern side effects

Get emergency medical help if you have signs of an allergic Reaction to Qtern: hives, itching, flaking or peeling skin; trouble swallowing, difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.

Stop taking this medicine and call your doctor at once if you have:

severe or ongoing pain in your joints;

serious skin reaction - itching, blisters, breakdown of the outer layer of skin;

ketoacidosis (too much acid in the blood) - nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;

pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;

dehydration symptoms - dizziness, weakness, feeling light-headed (like you might pass out); or

signs of a bladder infection - pain or burning when you urinate, increased urination, blood in your urine, pain in your pelvis or back.

Some people taking dapagliflozin have HAD bladder cancer, but it is not clear if this medicine was the actual cause.

Common Qtern side effects may include:

urination problems;

abnormal blood levels of cholesterol or triglycerides; or

runny nose, stuffy nose, sinus pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Qtern

You should not use Qtern if you have:

severe kidney disease (or if you are on dialysis); or

a history of severe allergic or skin reaction after taking dapagliflozin or saxagliptin.

To make sure Qtern is safe for you, tell your doctor if you have ever had:

kidney disease;

diabetic ketoacidosis;

liver disease;

bladder cancer;

bladder infections or other urination problems;

problems with your pancreas, including surgery;

gallstones;

high triglycerides (a type of fat in the blood);

alcoholism;

if you are on a low salt diet; or

if you are 65 or older.

Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.

You should not use Qtern during the second or third trimester of pregnancy.

You should not breast-feed while using this medicine.

Qtern is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Qtern

Usual Adult Dose for Diabetes Type 2:

Dapagliflozin 10 mg/saxagliptin 5 mg orally once a day in the morning Comments: -Volume depletion should be corrected prior to initiation. -This combination product should only be used in patients who tolerate dapagliflozin 10 mg per day. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who have inadequate control with dapagliflozin or who are already treated with Qtern.

Warnings

You should not use Qtern if you have severe kidney disease or if you are on dialysis.

Taking Qtern can make you dehydrated, which could cause you to feel weak or dizzy (especially when you stand up).

Stop taking Qtern and call your doctor at once if you have signs of a pancreatitis, such as severe pain in your upper stomach spreading to your back, with or without vomiting,

Dapagliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

What other drugs will affect Qtern

Qtern may not work as well when you use other medicines at the SAMe time. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all medicines you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.