Quinapril

Generic name: Quinapril
Brand names: Accupril
Dosage form: oral tablet (10 mg; 20 mg; 40 mg; 5 mg)
Drug class: Angiotensin Converting Enzyme Inhibitors

Usage of Quinapril

Quinapril is used in adults alone or in combination with other medications to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Quinapril is also used in adults together with other medications to treat heart failure.

Quinapril may also be used for purposes not listed in this medication guide.

Quinapril side effects

Get emergency medical help if you have signs of an allergic Reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Quinapril may cause serious side effects. Call your doctor at once if you have:

chest pain, fast, slow, or uneven heart rate;

a light-headed feeling, like you might pass out;

heart problems--swelling, rapid weight gain, feeling short of breath;

kidney problems--swelling, urinating less, feeling tired or short of breath;

liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), abnormal liver function tests;

signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or

high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects of quinapril may include:

headache;

nausea, vomiting, stomach pain;

cough; or

dizziness, tiredness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Quinapril

You should not use quinapril if you are allergic to it, or if:

have a history of angioedema; or

you are allergic to any other ACE inhibitor, such as Benazepril, Captopril, Enalapril, fosinopril, lisinopril, moexipril, perindopril, ramipril, or trandolapril.

Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking quinapril with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;

heart problems;

low blood pressure;

high blood levels of potassium (hyperkalemia);

if you are on a low-salt diet;

low white blood cell counts;

diabetes;

kidney disease (or if you are on dialysis); or

liver disease.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Ask a doctor if it is safe to breastfeed while using this medicine.

Relate drugs

How to use Quinapril

Usual Adult Dose for Hypertension:

Initial dose: 10 or 20 mg orally once a day in patients not on diureticsMaintenance dose: 20 to 80 mg orally per day, administered as a single dose or in two equally divided dosesUse:-Treatment of hypertension

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 5 mg orally twice a dayMaintenance dose: 20 to 40 mg orally per day administered in two equally divided dosesComments:-This dose may improve symptoms of heart failure, but increases in exercise duration have generally required higher doses.-If the initial dosage is well tolerated, patients should then be titrated at weekly intervals until an effective dose.Use:-Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis

Usual Geriatric Dose for Congestive Heart Failure:

10 mg orally once a dayComments: Dose should be titrated the SAMe way as for other adult patients.Uses:-Treatment of hypertension-Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis

Usual Geriatric Dose for Hypertension:

10 mg orally once a dayComments: Dose should be titrated the same way as for other adult patients.Uses:-Treatment of hypertension-Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis

Warnings

Do not use if you are pregnant. Stop using quinapril and tell your doctor right away if you become pregnant.

You should not use quinapril if you have ever had angioedema. Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).

What other drugs will affect Quinapril

Tell your doctor about all your other medicines, especially:

lithium;

a diuretic or "water pill";

gold injections to treat arthritis;

Temsirolimus, sirolimus, or everolimus; or

NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), Naproxen (Aleve), Celecoxib, diclofenac, Indomethacin, Meloxicam, and others.

This list is not complete. Other drugs may affect quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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