Radium Ra 223 dichloride

Generic name: Radium Ra 223 Dichloride
Brand names: Xofigo
Dosage form: intravenous solution (-)
Drug class: Therapeutic radiopharmaceuticals

Usage of Radium Ra 223 dichloride

Radium Ra 223 dichloride is used to treat prostate cancer that has spread to the bones and cannot be treated with surgery.

Radium Ra 223 dichloride may also be used for purposes not listed in this medication guide.

Radium Ra 223 dichloride side effects

Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Radium Ra 223 dichloride may cause serious side effects. Call your doctor at once if you have:

  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • a light-headed feeling, like you might pass out;
  • dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
  • low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing.
  • Common side effects of radium Ra 223 dichloride may include:

  • nausea, vomiting, diarrhea;
  • low blood cell counts; or
  • swelling in your hands or feet.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Radium Ra 223 dichloride

    Radium Ra 223 dichloride can harm an unborn baby or cause birth defects if you father a child while using this medicine. Use condoms while you are being treated with this medicine and for at least 6 months after treatment ends.

    Your sex partner should also use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose. Tell your doctor right away if a pregnancy occurs during this time.

    This medicine may affect fertility (your ability to have children). However, it is important to use birth control to prevent pregnancy because radium Ra 223 dichloride can harm an unborn baby.

    Relate drugs

    How to use Radium Ra 223 dichloride

    Usual Adult Dose for Prostate Cancer:

    50 kilobecquerel (kBq) or 1.35 microcurie per kg body weight, IV, every 4 weeksDuration of therapy: 6 dosesComments: See manufacturer's product information for complete dosing instructions including decay correction factor table and calculation of correct volume for dosing.Use: The treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases, and no known visceral metastatic disease.

    Warnings

    radium Ra 223 dichloride can increase your risk of bleeding or infection. You will need frequent medical tests.

    What other drugs will affect Radium Ra 223 dichloride

    You may have an increased risk of bone fractures or death if you are treated with radium Ra 223 dichloride while you are also taking another medicine for prostate cancer called abiraterone (Yonsa, Zytiga) in combination with prednisone or prednisolone (steroid medicine).

    Other drugs may affect radium Ra 223 dichloride, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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