Relenza

Generic name: Zanamivir

Usage of Relenza

Relenza is an antiviral medicine that blocks the actions of viruses in your body.

Relenza is used to treat flu symptoms caused by influenza virus in people who have had symptoms for less than 2 days.

Relenza may also be given to prevent influenza in people who may be exposed but do not yet have symptoms. Zanamivir will not treat the common cold.

Relenza should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.

Relenza side effects

Get emergency medical help if you have signs of an allergic reaction to Relenza: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people using Relenza (especially children) have had sudden unusual changes in mood or behavior. It is not certain that zanamivir is the exact cause of these symptoms. Even without using Relenza, anyone with influenza can have neurologic or behavioral symptoms. Call your doctor right away if the person using this medicine has:

sudden confusion;

trouble speaking;

tremors or shaking;

a seizure; or

hallucinations (hearing or seeing things that are not there).

Stop using this medicine and call your doctor at once if you have wheezing or severe breathing problems, or if you feel like you might pass out.

Common Relenza side effects may include:

headache, dizziness;

nausea, vomiting, diarrhea;

cough, wheezing, trouble breathing;

ear pain; or

cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Relenza

You should not use Relenza if you are allergic to zanamivir or to lactose (milk sugar).

Do not use Relenza to treat flu symptoms in a child younger than 7 years old. Children as young as 5 years old may use the medication to prevent flu symptoms.

To make sure Relenza is safe for you, tell your doctor if you have ever had:

asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition.

It is not known whether this medicine will harm an unborn baby. However, getting sick with influenza during pregnancy can cause complications leading to birth defects, low birth weight, preterm delivery, or stillbirth. Your doctor will decide whether you should use zanamivir if you are pregnant.

The Centers for Disease Control and Prevention (CDC) recommends that pregnant women may receive a yearly flu vaccine to prevent influenza. Relenza is not to be used in place of the yearly flu shot.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How to use Relenza

Usual Adult Dose for Influenza:

10 mg (2 inhalations) inhaled orally twice a day (12 hours apart) for 5 days If possible, 2 doses should be taken on the first day, provided there are at least 2 hours between the doses.

Usual Adult Dose for Influenza Prophylaxis:

10 mg (2 inhalations) inhaled orally once a day Duration: Household setting: 10 days Community outbreak: 28 days

Usual Pediatric Dose for Influenza:

7 years or older: 10 mg (2 inhalations) inhaled orally twice a day (12 hours apart) for 5 days If possible, 2 doses should be taken on the first day, provided there are at least 2 hours between the doses.

Usual Pediatric Dose for Influenza Prophylaxis:

5 years or older: 10 mg (2 inhalations) inhaled orally once a day Duration: Household setting: 10 days Community outbreak: 28 days

Warnings

Some people using Relenza have had sudden unusual changes in mood or behavior, most often in children. It is not certain that zanamivir is the exact cause. Even without using zanamivir, anyone with influenza can have neurologic or behavioral effects that may lead to confusion or hallucinations. Call your doctor right away if the person using this medicine has any signs of unusual thoughts or behavior.

Relenza should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.

Before using Relenza, tell your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition. Serious or life-threatening bronchospasm (difficulty breathing) and other effects on the lungs can occur while using this medicine. Stop using Relenza and call your doctor at once if you have wheezing or severe breathing problems. Do not use a nebulizer or ventilator to give this medicine. The inhalation powder should never be mixed with a liquid.

Treatment with this medicine should start as soon as possible when flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.

Do not use an inhaled nasal flu vaccine (FluMist) within 2 weeks before or 48 hours after using this medicine. Zanamivir may interfere with the drug action of FluMist, making the vaccine less effective. Follow your doctor's instructions.

What other drugs will affect Relenza

Other drugs may interact with zanamivir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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