Rexaphenac

Generic name: Diclofenac Topical
Drug class: Topical non-steroidal anti-inflammatories

Usage of Rexaphenac

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID).

Rexaphenac (for the skin) is used to treat joint pain caused by osteoarthritis. Rexaphenac is for use on the hands, wrists, elbows, knees, ankles, or feet. This medicine may not be effective in treating arthritis pain elsewhere in the body.

Pennsaid is for use only on the knees.

Solaraze is used to treat warty overgrowths of skin (actinic keratoses) on sun-exposed areas of the body.

Rexaphenac may also be used for purposes not listed in this medication guide.

Rexaphenac side effects

Get emergency medical help if you have signs of an allergic reaction (hives, sneezing, runny or stuffy nose, wheezing or trouble breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using diclofenac and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Stop using diclofenac and seek emergency medical attention if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Also call your doctor at once if you have:

a skin rash, no matter how mild;

swelling, rapid weight gain;

severe headache, blurred vision, pounding in your neck or ears;

little or no urination;

liver problems--nausea, diarrhea, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or

signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects of Rexaphenac may include:

heartburn, gas, stomach pain, nausea, vomiting;

diarrhea, constipation;

headache, dizziness, drowsiness;

stuffy nose;

itching, increased sweating;

increased blood pressure; or

skin redness, itching, dryness, scaling, or peeling where the medicine was applied.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Rexaphenac

Rexaphenac can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Rexaphenac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

You should not use this medicine if you are allergic to diclofenac (Voltaren, Cataflam, Flector, and others), or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Rexaphenac is not approved for use by anyone younger than 18 years old.

Tell your doctor if you have ever had:

heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

a heart attack, stroke, or blood clot;

stomach ulcers, bleeding in your stomach or intestines;

asthma;

liver or kidney disease; or

fluid retention.

Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine.

If you are pregnant, you should not take Rexaphenac unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Relate drugs

How to use Rexaphenac

Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if Rexaphenac gets in your eyes or mouth.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Do not apply Rexaphenac to an open skin wound, or on areas of infection, rash, burn, or peeling skin.

Store at room temperature away from moisture and heat. Do not freeze.

Warnings

Rexaphenac can increase your risk of fatal heart attack or stroke. Do not use Rexaphenac just before or after heart bypass surgery (coronary artery bypass graft, or CABG). This medicine may also cause stomach or intestinal bleeding, which can be fatal.

What other drugs will affect Rexaphenac

Ask your doctor before using diclofenac if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all your current medicines, especially:

cyclosporine;

lithium;

methotrexate;

a blood thinner (warfarin, Coumadin, Jantoven);

heart or blood pressure medication, including a diuretic or "water pill"; or

steroid medicine (prednisone and others).

This list is not complete and many other drugs may affect diclofenac. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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