Rezafungin

Generic name: Rezafungin
Brand names: Rezzayo
Dosage form: intravenous powder for injection (200 mg)
Drug class: Echinocandins

Usage of Rezafungin

Rezafungin is an antifungal medicine that is used to treat adults with candida (yeast) infections in the blood.

Rezafungin may also be used for purposes not listed in this medication guide.

Rezafungin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Rezafungin may cause serious side effects. Call your doctor at once if you have:

low blood potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

low blood magnesium--dizziness, irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, cough or choking feeling; or

low blood phosphate--seizure, confusion, bone pain, or muscle weakness.

Common side effects of rezafungin may include:

low blood levels of potassium, phosphate, or magnesium;

diarrhea, nausea, vomiting;

constipation, stomach pain;

pale skin, tiredness, feeling light-headed or short of breath, cold hands and feet; or

fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Rezafungin

You should not use rezafungin if you are allergic to rezafungin or similar medicines such as:

anidulafungin;

caspofungin; or

micafungin.

Tell your doctor if you have or have ever had liver disease.

It is not known if rezafungin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Relate drugs

How to use Rezafungin

Usual Adult Dose for Candidemia:

Loading dose: 400 mg once by IV infusion Maintenance dose: 200 mg once a week by IV infusion -Administer IV infusion over approximately one hour (250 mL/hr).-For infusion-related reactions, slow or pause infusion, and restart at a lower rate. Duration of therapy: Safety has not been established beyond 4 weekly dosesComments:-It is recommended to obtain cultures prior to initiating antifungal therapy; adjust treatment appropriately once culture results are known. -For IV use only; dilute prior to administration. Use: For the treatment of candidemia and invasive candidiasis in adult patients with limited or no alternative options; approval based on limited clinical safety and efficacy data.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Rezafungin

Other drugs may affect rezafungin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.