Sacrosidase

Generic name: Sacrosidase
Brand names: Sucraid
Dosage form: oral solution (8500 intl units/mL)
Drug class: Digestive enzymes

Usage of Sacrosidase

Sacrosidase is a yeast-based enzyme that replaces an enzyme called sucrase which is normally produced in the body. Sucrase helps the body breakdown and process certain sugars during digestion. In people who lack the sucrase enzyme, sugar can pass into the intestines where it can interact with bacteria. This can cause bloating, gas, stomach pain, and watery diarrhea.

Sacrosidase is used to treat sucrase deficiency that occurs in people with congenital sucrase-isomaltase deficiency (CSID). CSID is a genetic enzyme deficiency and sacrosidase will not cure this condition.

Do not use sacrosidase to treat any medical condition that has not been checked by your doctor. sacrosidase is not for use in treating general indigestion or stomach disorders caused by other conditions.

Sacrosidase may also be used for purposes not listed in this medication guide.

Sacrosidase side effects

Get emergency medical help if you have any of these signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Sacrosidase may cause serious side effects. Call your doctor at once if you have:

worsening stomach pain, nausea, vomiting, or diarrhea; or

feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Some of these side effects may be symptoms of your CSID condition and not actual side effects of sacrosidase.

Common side effects of sacrosidase may include:

stomach pain, mild nausea;

mild diarrhea, constipation;

sleep problems (insomnia);

headache; or

nervous feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Sacrosidase

You should not use this medicine if you are allergic to yeast, yeast products, glycerin (glycerol), or papain (Accuzyme, Ethezyme, Gladase, Kovia, and others).

To make sure sacrosidase is safe for you, tell your doctor if you have diabetes. Sacrosidase changes the way your body absorbs sugar and your glucose levels may change. Your doctor will tell you if any of your medication doses need to be changed.

FDA pregnancy category C. It is not known whether sacrosidase will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Tell your doctor if you are breast-feeding a baby while taking sacrosidase.

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How to use Sacrosidase

Usual Adult Dose for Sucrase-Isomaltase Deficiency:

Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or sNACkOver 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snackComment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with congenital sucrase-isomaltase deficiency (CSID)

Usual Pediatric Dose for Sucrase-Isomaltase Deficiency:

5 months and older:-Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or snack-Over 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snackComment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with CSID

Warnings

sacrosidase sometimes causes a severe allergic reaction. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

What other drugs will affect Sacrosidase

Other drugs may interact with sacrosidase, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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